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本文引用的文献

1
Magnesium stearate, a widely-used food additive, exhibits a lack of and genotoxic potential.硬脂酸镁,一种广泛使用的食品添加剂,显示出缺乏基因毒性潜力。 (原句中“a lack of and genotoxic potential”表述似乎不完整,推测可能是“a lack of genotoxic potential”,以上译文基于此推测翻译)
Toxicol Rep. 2017 Oct 16;4:554-559. doi: 10.1016/j.toxrep.2017.10.003. eCollection 2017.
2
The effect of coniine on presynaptic nicotinic receptors.毒芹碱对突触前烟碱型受体的作用。
Z Naturforsch C J Biosci. 2016;71(5-6):115-20. doi: 10.1515/znc-2015-0194.
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From fish poison to merck picrotoxin.从鱼毒到默克印防己毒素。
Anesthesiology. 2013 Jun;118(6):1263. doi: 10.1097/ALN.0b013e31829a0b4b.
4
The low-dose combination preparation Vertigoheel activates cyclic nucleotide pathways and stimulates vasorelaxation.低剂量组合制剂 Vertigoheel 可激活环核苷酸途径并刺激血管舒张。
Clin Hemorheol Microcirc. 2010;46(1):23-35. doi: 10.3233/CH-2010-1330.
5
The homeopathic preparation Vertigoheel versus Ginkgo biloba in the treatment of vertigo in an elderly population: a double-blinded, randomized, controlled clinical trial.顺势疗法制剂Vertigoheel与银杏叶治疗老年人群眩晕的对照研究:一项双盲、随机、对照临床试验
J Altern Complement Med. 2005 Feb;11(1):155-60. doi: 10.1089/acm.2005.11.155.
6
Homeopathy.顺势疗法
Med Clin North Am. 2002 Jan;86(1):47-62. doi: 10.1016/s0025-7125(03)00071-3.
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Complementary and alternative medicine in otolaryngology.耳鼻咽喉科中的补充与替代医学。
Laryngoscope. 2001 Aug;111(8):1383-9. doi: 10.1097/00005537-200108000-00013.
8
Homeopathic vs conventional treatment of vertigo: a randomized double-blind controlled clinical study.顺势疗法与传统疗法治疗眩晕:一项随机双盲对照临床研究。
Arch Otolaryngol Head Neck Surg. 1998 Aug;124(8):879-85. doi: 10.1001/archotol.124.8.879.
9
The clinical efficacy of Vertigoheel in the treatment of vertigo of various etiology.倍他司汀治疗各种病因所致眩晕的临床疗效。
Panminerva Med. 1993 Jun;35(2):101-4.
10
A method for estimating the probability of adverse drug reactions.一种估算药物不良反应概率的方法。
Clin Pharmacol Ther. 1981 Aug;30(2):239-45. doi: 10.1038/clpt.1981.154.

威蒂格内耳眩晕症引发的精神病:一例患者病例报告。

Vertigoheel induced psychosis: A patient case report.

作者信息

O'Connell Megan, Hunt Elizabeth, VandenBerg Amy

机构信息

PGY-4 Psychiatry Resident, Michigan Medicine, Ann Arbor, Michigan.

Clinical Pharmacy Specialist, Psychiatry and Neurology, Michigan Medicine, Ann Arbor, Michigan.

出版信息

Ment Health Clin. 2021 Jan 8;11(1):31-34. doi: 10.9740/mhc.2021.01.031. eCollection 2021 Jan.

DOI:10.9740/mhc.2021.01.031
PMID:33505824
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7800325/
Abstract

OBJECTIVE

To describe a case of a patient who developed psychosis after ingestion of Vertigoheel for treatment of dizziness.

CASE SUMMARY

A 28-year-old male with no psychiatric history presented with 5 days of worsening depression and psychosis. He denied current use of prescription medications, alcohol, or illicit substances. Approximately 2 weeks prior, while visiting family in Germany, he developed dizziness. A provider in Germany prescribed Vertigoheel, 1 tablet to be taken every hour until symptom improvement. This did not improve his dizziness but did cause him to feel as if he were "in a dream." He stopped taking the medication after 2 days but continued to feel amotivated with decreased appetite and insomnia. Several days later, he developed ego-dystonic auditory hallucinations. He returned to the United States; was admitted to an inpatient psychiatric unit for 4 days; and given olanzapine 5 mg at bedtime, lorazepam 1 mg every evening, and melatonin 6 mg every evening. He experienced gradual improvement in symptoms and was discharged with olanzapine 5 mg daily and outpatient follow-up.

DISCUSSION

Vertigoheel is a homeopathic preparation containing ambra grisea, , , and petroleum. Psychosis was not reported in any of the randomized controlled trials evaluating the use of Vertigoheel for treatment of vertigo. A literature search revealed no published reports of psychosis as a result of administration of any components of Vertigoheel.

CONCLUSION

A possible causal relationship was observed between the homeopathic supplement Vertigoheel and an acute episode of psychosis in a young male patient with no comorbidities.

摘要

目的

描述一例患者在服用眩晕停(Vertigoheel)治疗头晕后出现精神病性症状的病例。

病例摘要

一名28岁无精神病史的男性,出现了5天来逐渐加重的抑郁和精神病性症状。他否认目前使用处方药、酒精或非法药物。大约2周前,他在德国探亲时出现头晕。德国的一名医生开了眩晕停,每小时服用1片,直至症状改善。这并未改善他的头晕症状,但却使他感觉自己“像在梦中”。2天后他停止服药,但仍持续感到动力缺乏、食欲减退和失眠。几天后,他出现了与自我不协调的幻听。他返回美国,入住一家住院精神科病房4天,睡前给予奥氮平5毫克、每晚给予劳拉西泮1毫克以及每晚给予褪黑素6毫克。他的症状逐渐改善,出院时带了每日5毫克的奥氮平并进行门诊随访。

讨论

眩晕停是一种顺势疗法制剂,含有琥珀、……和石油。在评估眩晕停用于治疗眩晕的任何随机对照试验中均未报告精神病性症状。文献检索未发现因服用眩晕停的任何成分而导致精神病性症状的已发表报告。

结论

在一名无合并症的年轻男性患者中,观察到顺势疗法补充剂眩晕停与一次急性精神病发作之间可能存在因果关系。