O'Connell Megan, Hunt Elizabeth, VandenBerg Amy
PGY-4 Psychiatry Resident, Michigan Medicine, Ann Arbor, Michigan.
Clinical Pharmacy Specialist, Psychiatry and Neurology, Michigan Medicine, Ann Arbor, Michigan.
Ment Health Clin. 2021 Jan 8;11(1):31-34. doi: 10.9740/mhc.2021.01.031. eCollection 2021 Jan.
To describe a case of a patient who developed psychosis after ingestion of Vertigoheel for treatment of dizziness.
A 28-year-old male with no psychiatric history presented with 5 days of worsening depression and psychosis. He denied current use of prescription medications, alcohol, or illicit substances. Approximately 2 weeks prior, while visiting family in Germany, he developed dizziness. A provider in Germany prescribed Vertigoheel, 1 tablet to be taken every hour until symptom improvement. This did not improve his dizziness but did cause him to feel as if he were "in a dream." He stopped taking the medication after 2 days but continued to feel amotivated with decreased appetite and insomnia. Several days later, he developed ego-dystonic auditory hallucinations. He returned to the United States; was admitted to an inpatient psychiatric unit for 4 days; and given olanzapine 5 mg at bedtime, lorazepam 1 mg every evening, and melatonin 6 mg every evening. He experienced gradual improvement in symptoms and was discharged with olanzapine 5 mg daily and outpatient follow-up.
Vertigoheel is a homeopathic preparation containing ambra grisea, , , and petroleum. Psychosis was not reported in any of the randomized controlled trials evaluating the use of Vertigoheel for treatment of vertigo. A literature search revealed no published reports of psychosis as a result of administration of any components of Vertigoheel.
A possible causal relationship was observed between the homeopathic supplement Vertigoheel and an acute episode of psychosis in a young male patient with no comorbidities.
描述一例患者在服用眩晕停(Vertigoheel)治疗头晕后出现精神病性症状的病例。
一名28岁无精神病史的男性,出现了5天来逐渐加重的抑郁和精神病性症状。他否认目前使用处方药、酒精或非法药物。大约2周前,他在德国探亲时出现头晕。德国的一名医生开了眩晕停,每小时服用1片,直至症状改善。这并未改善他的头晕症状,但却使他感觉自己“像在梦中”。2天后他停止服药,但仍持续感到动力缺乏、食欲减退和失眠。几天后,他出现了与自我不协调的幻听。他返回美国,入住一家住院精神科病房4天,睡前给予奥氮平5毫克、每晚给予劳拉西泮1毫克以及每晚给予褪黑素6毫克。他的症状逐渐改善,出院时带了每日5毫克的奥氮平并进行门诊随访。
眩晕停是一种顺势疗法制剂,含有琥珀、……和石油。在评估眩晕停用于治疗眩晕的任何随机对照试验中均未报告精神病性症状。文献检索未发现因服用眩晕停的任何成分而导致精神病性症状的已发表报告。
在一名无合并症的年轻男性患者中,观察到顺势疗法补充剂眩晕停与一次急性精神病发作之间可能存在因果关系。