Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269, USA.
Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269, USA; Department of Chemical and Biomolecular Engineering, University of Connecticut, Storrs, CT 06269, USA; Institute of Material Sciences, University of Connecticut, Storrs, CT 06269, USA.
Int J Pharm. 2021 Mar 1;596:120284. doi: 10.1016/j.ijpharm.2021.120284. Epub 2021 Jan 26.
Triboelectric charging is defined as the phenomenon of charge transfer between two different material surfaces when they are brought into contact and separated. The focus of this research is the development of a Discrete Element Method (DEM) based simulation model to predict tribocharging during hopper discharge. Due to decreased particle-wall interactions and reduced particle wall contact times, net charges generated during hopper discharge are low. The simulation model confirmed this effect and was implemented to predict the triboelectric behavior of glass beads and MCC particles during hopper flow, along with the prediction of percent charged and uncharged particles. Approximately one-third of the particles were predicted to remain uncharged during the hopper discharge simulations for mono-dispersed particles, thus rendering a comparatively high amount of charge distribution into a small concentration of materials. The DEM model acted as a tool to predict charges that can be generated during hopper discharge at a specified geometry, with a potential to mitigate particle charging, when used for appropriate selection of hopper angles, and hopper wall materials.
摩擦起电是指当两个不同材料的表面接触和分离时,电荷在它们之间转移的现象。本研究的重点是开发一种基于离散元法(DEM)的模拟模型,以预测料斗卸料过程中的摩擦带电现象。由于颗粒与壁面的相互作用减弱以及颗粒与壁面接触时间减少,料斗卸料过程中产生的净电荷较低。模拟模型证实了这一效应,并被用于预测玻璃珠和 MCC 颗粒在料斗流动过程中的摩擦带电行为,以及带电和不带电颗粒的预测。对于单分散颗粒,约有三分之一的颗粒在料斗卸料模拟中保持不带电,因此将相对较高的电荷量分布到少量的材料中。DEM 模型可用作预测特定几何形状下料斗卸料时可能产生的电荷的工具,如果适当选择料斗角度和料斗壁材料,有可能减轻颗粒充电。