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螺旋断层调强放疗中的专用质量保证用出射探测器的剂量验证。

TomoEQA: Dose verification for patient-specific quality assurance in helical tomotherapy using an exit detector.

机构信息

Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, Republic of Korea.

Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, Republic of Korea.

出版信息

Phys Med. 2021 Feb;82:1-6. doi: 10.1016/j.ejmp.2020.12.021. Epub 2021 Jan 25.

Abstract

PURPOSE

Existing phantom-less quality assurance (QA) platforms does not provide patient-specific QA for helical tomotherapy (HT). A new system, called TomoEQA, is presented to facilitate this using the leaf open time (LOT) of a binary multi-leaf collimator, as measured by an exit detector.

METHODS

TomoEQA was designed to provide measurement-based LOTs based on detector data and to generate a new digital imaging and communication in medicine (DICOM) dataset that includes the measured LOTs for use by secondary check platforms. To evaluate the system, 20 patient-specific QAs were performed using the program in Mobius3D software, and the results were compared to conventional phantom-based QA results.

RESULTS

From our assessment, most of the differences between the planned and measured (or calculated) data, excluding one case, were within the acceptance criteria comparing with those of conventional QA. Regarding the gamma analysis, all results considered in this study were within the acceptance criteria. In addition, the developed system was performed for a failed case and showed approximately the same trends as the conventional approach.

CONCLUSIONS

TomoEQA could perform patient-specific QAs of HT using Mobius3D and provide reliable patient-specific QAs results by evaluating point dose errors and 3D gamma passing rates. TomoEQA could also distinguish whether an intensity-modulated radiation therapy plan failed or not.

摘要

目的

现有的无模体质量保证(QA)平台无法为螺旋断层放疗(HT)提供患者特异性 QA。本文提出了一种新的系统,称为 TomoEQA,它使用二进制多叶准直器的叶开时间(LOT)作为测量值,通过出口探测器来实现这一点。

方法

TomoEQA 旨在根据探测器数据提供基于测量的 LOT,并生成一个新的数字成像和通信在医学(DICOM)数据集,其中包括用于二级检查平台的测量 LOT。为了评估该系统,在 Mobius3D 软件中使用该程序进行了 20 例患者特异性 QA,将结果与传统的基于模体的 QA 结果进行比较。

结果

从我们的评估来看,除了一个病例外,计划值与测量值(或计算值)之间的大多数差异都在与传统 QA 相比的接受标准范围内。关于伽马分析,本研究中考虑的所有结果都在接受标准范围内。此外,该开发系统还对一个失败的病例进行了处理,结果与传统方法的趋势大致相同。

结论

TomoEQA 可以使用 Mobius3D 对 HT 进行患者特异性 QA,并通过评估点剂量误差和 3D 伽马通过率来提供可靠的患者特异性 QA 结果。TomoEQA 还可以区分调强放疗计划是否失败。

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