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美国印第安人和阿拉斯加原住民的阿片类药物使用障碍治疗药物:全国样本中的供应和使用情况。

Medications for opioid use disorder among American Indians and Alaska natives: Availability and use across a national sample.

机构信息

Department of Population Health, NYU Grossman School of Medicine, New York, NY, USA.

Cherokee Nation Behavioral Health, Tahlequah, OK, USA; Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public, Health, Baltimore, MD, USA.

出版信息

Drug Alcohol Depend. 2021 Mar 1;220:108512. doi: 10.1016/j.drugalcdep.2021.108512. Epub 2021 Jan 19.

Abstract

BACKGROUND

American Indians and Alaska Natives (AI/ANs) are disproportionately affected by the opioid overdose crisis. Treatment with medications for opioid use disorder (MOUD) can significantly reduce overdose risk, but no national studies to date have reported on the extent to which AI/ANs access these treatments overall and in relation to other groups.

METHODS

The current study used two national databases - the 2018 National Survey on Substance Abuse Treatment Services and the 2017 Treatment Episode Dataset - to estimate the extent to which MOUD is available and used among AI/ANs across the U.S.

RESULTS

We found that facilities serving AI/ANs (N = 1,532) offered some MOUD at similar rates as other facilities (N = 13,277) (39.6 vs. 40.6 %, p = 0.435) but were less likely to offer the standard of care with buprenorphine or methadone maintenance (22.4 % vs. 27.6 %, p < 0.001). AI/AN clients in specialty treatment (N = 8,136) exhibited slightly higher MOUD use (40.0 % vs. 38.6 %, p = 0.009) relative to other race groups (N = 673,938). AI/AN clients were also more likely to exhibit greater prescription opioid use and methamphetamine co-use relative to other groups. AI/AN clients in the South (aOR:0.23[95 %CI: 0.19-0.28] or referred by criminal justice sources (aOR:0.13[95 %CI: 0.11-0.16] were least likely to receive MOUD.

CONCLUSIONS

We conclude that most AI/ANs in specialty treatment do not receive medications for opioid use disorder, and that rates of MOUD use are similar to those of other race groups. Efforts to expand MOUD among AI/ANs that are localized and cater to unique characteristics of this population are gravely needed.

摘要

背景

美洲印第安人和阿拉斯加原住民(AI/AN)受到阿片类药物过量危机的影响不成比例。使用治疗阿片类药物使用障碍(MOUD)的药物可以显著降低过量风险,但迄今为止,没有全国性的研究报告 AI/AN 总体上以及与其他群体相比,获得这些治疗的程度。

方法

本研究使用了两个国家数据库 - 2018 年国家药物滥用治疗服务调查和 2017 年治疗事件数据集 - 来估计美国各地 AI/AN 获得和使用 MOUD 的程度。

结果

我们发现,为 AI/AN 服务的设施(N = 1532)提供 MOUD 的比例与其他设施相似(39.6% 与 40.6%,p = 0.435),但提供丁丙诺啡或美沙酮维持治疗的标准比例较低(22.4% 与 27.6%,p < 0.001)。在专科治疗中(N = 8136)的 AI/AN 患者表现出略高的 MOUD 使用(40.0% 与 38.6%,p = 0.009),相对其他种族群体(N = 673938)。与其他群体相比,AI/AN 患者的处方类阿片药物使用和甲基苯丙胺共用药也更为常见。与其他群体相比,来自南部地区(aOR:0.23[95%CI:0.19-0.28])或由刑事司法来源转介(aOR:0.13[95%CI:0.11-0.16])的 AI/AN 患者最不可能接受 MOUD。

结论

我们的结论是,大多数在专科治疗中的 AI/AN 患者没有接受治疗阿片类药物使用障碍的药物,MOUD 的使用率与其他种族群体相似。迫切需要针对 AI/AN 人群的特点,开展本地化的扩大 MOUD 治疗的努力。

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