Department of Otorhinolaryngology, Yiwu central Hospital, 699 Jiangdong Road, Yiwu city, 322000, Zhejiang Province, China.
J Otolaryngol Head Neck Surg. 2021 Jan 28;50(1):6. doi: 10.1186/s40463-021-00496-z.
Chronic tympanic membrane (TM) perforation associated with ventilation tube (VT) insertion was commonly encountered in pediatric patients with chronic otitis media with effusion (COME) treatment and eustachian tube dysfunction. The persistent perforation require surgical closure by myringoplasty. Song JS et al. recently a paper entitled: "Evaluating short and long term outcomes following pediatric myringoplasty with gelfoam graft for tympanic membrane perforation following ventilation tube insertion." In their study, the authors performed gelfoam myringoplasty to repair the perforations following VT insertion in children and compare the successful TM closure rate among different graft materials. The authors believed that gelfoam alone was superior to hyaluronic acid (HA), tragal cartilage (TC), and gelfoam-plus-temporal fascia (TF). The sample size is unbalanced and incommensurable between gelfoam and other graft materials. In addition, a confounding factor was added in the gelfoam group, thereby affected the assessment of TM closure. Thus, the conclusion is not rigorous and scientific.
慢性鼓膜（TM）穿孔与通气管（VT）插入相关，在患有慢性中耳炎伴积液（COME）和咽鼓管功能障碍的儿科患者中很常见。持续性穿孔需要通过鼓室成形术进行手术修复。Song JS 等人最近发表了一篇题为：“在儿童鼓室成形术中使用明胶海绵移植物治疗 VT 插入后鼓膜穿孔的短期和长期结果评估。”在他们的研究中，作者对 VT 插入后鼓膜穿孔的儿童进行了明胶海绵鼓室成形术，并比较了不同移植物材料的 TM 闭合率。作者认为，明胶海绵单独使用优于透明质酸（HA）、耳屏软骨（TC）和明胶海绵加颞筋膜（TF）。明胶海绵和其他移植物材料之间的样本量不平衡且不可比。此外，在明胶海绵组中加入了一个混杂因素，从而影响了 TM 闭合的评估。因此，该结论不严格、不科学。
