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在肾移植前进行心脏筛查——良好的意愿而非确凿的证据决定了实践。

Cardiac screening prior to renal transplantation-good intentions, rather than good evidence, dictate practice.

机构信息

Institute of Cardiovascular and Medical Sciences, University of Glasgow, Scotland; Glasgow Renal and Transplant Unit, Queen Elizabeth University Hospital, Glasgow, Scotland.

Institute of Cardiovascular and Medical Sciences, University of Glasgow, Scotland; Glasgow Renal and Transplant Unit, Queen Elizabeth University Hospital, Glasgow, Scotland.

出版信息

Kidney Int. 2021 Feb;99(2):306-308. doi: 10.1016/j.kint.2020.10.043.

DOI:10.1016/j.kint.2020.10.043
PMID:33509350
Abstract

Cardiovascular disease is the leading cause of death in kidney transplant recipients in many transplant registries. An analysis of transplant recipients from the United Kingdom using propensity score matching (PSM) suggests there are limited or no benefits to cardiovascular screening before transplant listing. We suggest that short of a randomized controlled trial (RCT) in this area, these data are sufficient to suggest that transplant centers should reflect on their current protocols for cardiovascular workup required before transplantation.

摘要

心血管疾病是许多移植注册中心中肾移植受者的主要死亡原因。 使用倾向评分匹配(PSM)对来自英国的移植受者进行的分析表明,在移植登记前进行心血管筛查的益处有限或没有。 我们建议,除非在该领域进行随机对照试验(RCT),否则这些数据足以表明移植中心应反思其当前的移植前心血管检查所需的方案。

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Kidney Int. 2021 Feb;99(2):306-308. doi: 10.1016/j.kint.2020.10.043.
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Eur Heart J. 2023 Apr 1;44(13):1157-1166. doi: 10.1093/eurheartj/ehac825.
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Propensity Score and Instrumental Variable Techniques in Observational Transplantation Studies: An Overview and Worked Example Relating to Pre-Transplant Cardiac Screening.
倾向性评分和工具变量技术在观察性移植研究中的应用:概述及与移植前心脏筛查相关的实例分析。
Transpl Int. 2022 Jun 27;35:10105. doi: 10.3389/ti.2022.10105. eCollection 2022.
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Contrast Media Mol Imaging. 2022 May 5;2022:3001780. doi: 10.1155/2022/3001780. eCollection 2022.
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