National Laboratory Astana, Nazarbayev University, Nur-Sultan, Kazakhstan.
MOE Key Laboratory of Contemporary Anthropology and B&R International Joint Laboratory for Eurasian Anthropology, School of Life Sciences, Fudan University, Shanghai, China.
J Hum Genet. 2021 Jul;66(7):707-716. doi: 10.1038/s10038-021-00901-5. Epub 2021 Jan 29.
Western Kazakhstan is populated by three clans totaling 2 million people. Since the clans are patrilineal, the Y-chromosome is the most informative genetic system for tracing their origin. We genotyped 40 Y-SNP and 17 Y-STR markers in 330 Western Kazakhs. High phylogenetic resolution within haplogroup C2a1a2-M48 was achieved by using additional SNPs. Three lines of evidence indicate that the Alimuly and Baiuly clans (but not the Zhetiru clan) have a common founder placed 700 ± 200 years back by the STR data and 500 ± 200 years back by the sequencing data. This supports traditional genealogy claims about the descent of these clans from Emir Alau, who lived 650 years ago and whose lineage might be carried by two-thirds of Western Kazakhs. There is accumulation of specific haplogroups in the subclans representing other lineages, confirming that the clan structure corresponds with the paternal genetic structure of the steppe population.
哈萨克斯坦西部有三个部落，总人口约为 200 万。由于这些部落是父系社会，因此 Y 染色体是追踪其起源的最具信息量的遗传系统。我们对 330 名哈萨克斯坦西部人进行了 40 个 Y-SNP 和 17 个 Y-STR 标记的基因分型。通过使用额外的 SNP，我们在单倍群 C2a1a2-M48 内实现了高系统发育分辨率。有三条证据表明，Alimuly 和 Baiuly 部落（但不是 Zhetiru 部落）有一个共同的祖先，根据 STR 数据可以追溯到 700±200 年前，根据测序数据可以追溯到 500±200 年前。这支持了关于这些部落是从 650 年前的埃米尔·阿劳（Emir Alau）那里传承下来的传统族谱主张，他的后裔可能由三分之二的哈萨克斯坦西部人传承。在代表其他血统的子部落中积累了特定的单倍群，这证实了部落结构与草原人口的父系遗传结构相对应。
