Department of Surgery, Hospital of the University of Pennsylvania, 3400 Spruce Street, 5 Silverstein, Philadelphia, PA, 19104, USA.
Division of Endocrine and Oncologic Surgery, Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
World J Surg. 2021 Apr;45(4):946-954. doi: 10.1007/s00268-021-05958-z. Epub 2021 Jan 28.
The COVID-19 pandemic has resulted in large-scale healthcare restrictions to control viral spread, reducing operating room censuses to include only medically necessary surgeries. The impact of restrictions on which patients undergo surgical procedures and their perioperative outcomes is less understood.
Adult patients who underwent medically necessary surgical procedures at our institution during a restricted operative period due to the COVID-19 pandemic (March 23-April 24, 2020) were compared to patients undergoing procedures during a similar time period in the pre-COVID-19 era (March 25-April 26, 2019). Cardinal matching and differences in means were utilized to analyze perioperative outcomes.
857 patients had surgery in 2019 (pre-COVID-19) and 212 patients had surgery in 2020 (COVID-19). The COVID-19 era cohort had a higher proportion of patients who were male (61.3% vs. 44.5%, P < 0.0001), were White (83.5% vs. 68.7%, P < 0.001), had private insurance (62.7% vs. 54.3%, p 0.05), were ASA classification 4 (10.9% vs. 3%, P < 0.0001), and underwent oncologic procedures (69.3% vs. 42.7%, P < 0.0001). Following 1:1 cardinal matching, COVID-19 era patients (N = 157) had a decreased likelihood of discharge to a nursing facility (risk difference-8.3, P < 0.0001) and shorter median length of stay (risk difference-0.6, p 0.04) compared to pre-COVID-19 era patients. There was no difference between the two patient cohorts in overall morbidity and 30-day readmission.
COVID-19 restrictions on surgical operations were associated with a change in the racial and insurance demographics in patients undergoing medically necessary surgical procedures but were not associated with worse postoperative morbidity. Further study is necessary to better identify the causes for patient demographic differences.
COVID-19 大流行导致大规模医疗限制以控制病毒传播,减少手术室的手术数量,只包括医疗必需的手术。限制措施对接受手术的患者及其围手术期结局的影响尚不清楚。
将我院在 COVID-19 大流行期间(2020 年 3 月 23 日至 4 月 24 日)因限制手术而接受医疗必需手术的成年患者与在 COVID-19 前时期(2019 年 3 月 25 日至 4 月 26 日)接受手术的患者进行比较。采用基数匹配和均值差异分析围手术期结局。
2019 年有 857 例患者接受手术(COVID-19 前),2020 年有 212 例患者接受手术(COVID-19 期间)。COVID-19 期间的患者中,男性(61.3% vs. 44.5%,P<0.0001)、白人(83.5% vs. 68.7%,P<0.001)、私人保险(62.7% vs. 54.3%,P<0.05)、ASA 分级 4(10.9% vs. 3%,P<0.0001)和接受肿瘤手术(69.3% vs. 42.7%,P<0.0001)的比例更高。进行 1:1 基数匹配后,COVID-19 期间的患者(N=157)与 COVID-19 前期间的患者相比,出院到疗养院的可能性降低(风险差异-8.3,P<0.0001),中位住院时间缩短(风险差异-0.6,P<0.04)。两组患者的总发病率和 30 天再入院率无差异。
COVID-19 对手术的限制与接受医疗必需手术的患者种族和保险统计数据的变化有关,但与术后发病率增加无关。需要进一步研究以更好地确定患者人口统计学差异的原因。