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成人桥小脑角蛛网膜囊肿手术后的客观改善。

Objective improvement in adults with cerebellopontine angle arachnoid cysts after surgical treatment.

机构信息

Department of Neurosurgery - AP-HP, Hôpitaux Universitaires Pitié Salpêtrière-Charles Foix, 47-83 boulevard de l'hôpital, 75013, Paris, France.

Sorbonne Université, APHP.Sorbonne Université, Groupe Hospitalo-Universitaire Pitié-Salpêtrière, Paris, France.

出版信息

Acta Neurochir (Wien). 2021 Mar;163(3):753-758. doi: 10.1007/s00701-021-04721-6. Epub 2021 Jan 29.

DOI:10.1007/s00701-021-04721-6
PMID:33511461
Abstract

BACKGROUND

Intracranial arachnoid cysts are extra-axial benign lesions mainly found in the middle cerebral fossa. Rare case series report various cranial nerve dysfunctions associated with cerebellopontine angle (CPA) cysts and there is no consensus with regard to their surgical management; some reports claiming that subjective improvement in adults with intracranial arachnoid cysts cannot justify surgical treatment.

METHODS

This retrospective study included all 12 consecutive adult patients treated by microsurgical fenestration for symptomatic CPA arachnoid cysts between 2010 and 2019 and using a retrosigmoid approach. Demographic, clinical, surgical, and radiological data were collected from medical files.

RESULTS

The main symptoms were audiovestibular in 9 patients (75%) complaining of dizziness and 6 patients (50%) with hearing loss. In addition, 3 patients (25%) reported tinnitus, 3 patients (25%) presented vasovagal syncope, and 1 patient (8.3%) reported facial pain. Surgery improved 5 patients (83%) with pre-operative hearing loss, 7 patients (78%) reporting dizziness, and all patients with vasovagal syncope. All of the patients recovered from at least one symptom. No recurrence was observed with a mean follow-up of 5.5 years.

CONCLUSION

Although most arachnoid cysts are asymptomatic, the CPA location may lead to cranial nerve impairments. Microsurgical fenestration seems to be a simple, safe, and effective technique.

摘要

背景

颅内蛛网膜囊肿是一种主要位于大脑中动脉的外轴良性病变。罕见的病例系列报告显示,各种颅神经功能障碍与桥小脑角(CPA)囊肿有关,对于它们的手术治疗尚无共识;一些报告称,颅内蛛网膜囊肿患者的主观改善不能证明手术治疗是合理的。

方法

本回顾性研究纳入了 2010 年至 2019 年间连续 12 例成人患者,这些患者因有症状的 CPA 蛛网膜囊肿接受了显微手术开窗治疗,采用了经乙状窦后入路。从病历中收集了人口统计学、临床、手术和影像学数据。

结果

9 例患者(75%)主要表现为听觉前庭症状,表现为头晕,6 例患者(50%)出现听力损失。此外,3 例患者(25%)有耳鸣,3 例患者(25%)有血管迷走性晕厥,1 例患者(8.3%)有面部疼痛。手术改善了 5 例(83%)术前听力丧失的患者,7 例(78%)有头晕的患者,以及所有有血管迷走性晕厥的患者。所有患者均至少从一种症状中恢复。平均随访 5.5 年后未见复发。

结论

尽管大多数蛛网膜囊肿是无症状的,但 CPA 位置可能导致颅神经损伤。显微手术开窗似乎是一种简单、安全、有效的技术。

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Acta Neurochir (Wien). 2021 Mar;163(3):753-758. doi: 10.1007/s00701-021-04721-6. Epub 2021 Jan 29.
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Arachnoid cysts of the cerebellopontine angle: diagnosis and surgery.桥小脑角蛛网膜囊肿:诊断与手术
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引用本文的文献

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Symptomatic arachnoid cysts in adults: illustrative cases.成人症状性蛛网膜囊肿:病例展示
J Neurosurg Case Lessons. 2024 Dec 2;8(23). doi: 10.3171/CASE24428.
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Improvement in Hearing Loss Following Posterior Fossa Arachnoid Cyst Fenestration: A Case Study.后颅窝蛛网膜囊肿开窗术后听力损失的改善:病例报告
Cureus. 2024 Jan 6;16(1):e51750. doi: 10.7759/cureus.51750. eCollection 2024 Jan.
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Tinnitus Triggered by a Cerebellopontine Arachnoid Cyst in an Adolescent.青少年桥脑小脑角蛛网膜囊肿引发的耳鸣。
Am J Case Rep. 2022 Nov 28;23:e938294. doi: 10.12659/AJCR.938294.