Bergmanson J P, Pitts D G, Chu L W
Institute for Contact Lens Research, University of Houston, College of Optometry, TX 77004.
J Am Optom Assoc. 1988 Mar;59(3):178-82.
Ultraviolet radiation (UVR) has been demonstrated to be harmful to the cornea, the lens and the retina. Recent research has indicated that, in addition to the epithelial trauma found in UVR-induced keratitis, the deeper corneal layers are also involved. Since trauma to keratocytes and endothelial cells can result in permanent damage or cell loss, it is imperative to protect eyes against excessive dosages of UVR. Standard hydrogel contact lenses (Vistamarc normal) and newly developed UV-filtering hydrogel lenses (Vistakon UV-BLOC) were fitted on five rabbits and compared in protection from harmful UVR (300 nm). The eyes that wore the UV-filtering lens maintained normal corneas; however, the eyes that wore the standard hydrogel lens showed pronounced epithelial, stromal and endothelial changes. We concluded that the UV-filtering lens effectively absorbed the hazardous UV radiation while the standard soft lens provided little protection.
紫外线辐射(UVR)已被证明对角膜、晶状体和视网膜有害。最近的研究表明,除了紫外线诱导的角膜炎中发现的上皮损伤外,角膜更深层也会受到影响。由于角膜细胞和内皮细胞的损伤会导致永久性损伤或细胞丢失,因此保护眼睛免受过量紫外线辐射至关重要。将标准水凝胶隐形眼镜(Vistamarc normal)和新开发的紫外线过滤水凝胶隐形眼镜(Vistakon UV-BLOC)分别佩戴在5只兔子眼睛上,比较它们对有害紫外线辐射(300纳米)的防护效果。佩戴紫外线过滤镜片的眼睛角膜保持正常;然而,佩戴标准水凝胶镜片的眼睛出现了明显的上皮、基质和内皮变化。我们得出结论,紫外线过滤镜片能有效吸收有害的紫外线辐射,而标准软性镜片几乎没有防护作用。