Spinner Christoph D, Barton Jürgen, Biever Paul, Klein Matthias, Rieg Siegbert, Schneider Jochen, Thoden Jan, Wagner Dirk, Kern Winfried V
Technische Universität München, Fakultät für Medizin, Klinikum rechts der Isar, Klinik und Poliklinik für Innere Medizin II, München.
Klinikum der Ludwig-Maximilians-Universität Klinikum, Medizinische Klinik und Poliklinik V, München.
Dtsch Med Wochenschr. 2021 Feb;146(3):162-166. doi: 10.1055/a-1302-3530. Epub 2021 Jan 29.
Corticosteroids have been found as useful adjunctive therapy in patients with various infections and hyperinflammation-associated disease. They are recommended in practice guidelines for patients with tuberculous and pneumococcal meningitis and patients with immune reconstitution syndrome associated with antiretroviral therapy. A new indication is severe COVID-19. Evidence from clinical trials is insufficient to allow the routine use of steroids among patients with septic shock, community-acquired pneumonia or tuberculous pericarditis.
皮质类固醇已被发现是各种感染和与炎症过度相关疾病患者的有用辅助治疗方法。在结核病和肺炎球菌性脑膜炎患者以及与抗逆转录病毒治疗相关的免疫重建综合征患者的实践指南中推荐使用。一个新的适应证是重症新型冠状病毒肺炎。临床试验证据不足以支持在感染性休克、社区获得性肺炎或结核性心包炎患者中常规使用类固醇。
