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实验室饲养的多产乳鼠的血液学和临床化学参考范围()。

Hematology and Clinical Chemistry Reference Ranges for Laboratory-Bred Natal Multimammate Mice ().

机构信息

ZBS5-Biosafety Level-4 Laboratory, Robert Koch-Institute, 13353 Berlin, Germany.

International Center for Excellence in Research, Malaria Research and Training Center, Faculty of Medicine, Pharmacy and Dentistry, University of Sciences, Techniques and Technologies of Bamako, Bamako 91094, Mali.

出版信息

Viruses. 2021 Jan 27;13(2):187. doi: 10.3390/v13020187.

Abstract

Laboratory-controlled physiological data for the multimammate rat () are scarce, despite this species being a known reservoir and vector for zoonotic viruses, including the highly pathogenic Lassa virus, as well as other arenaviruses and many species of bacteria. For this reason, is an important rodent for the study of host-virus interactions within laboratory settings. Herein, we provide basic blood parameters for age- and sex-distributed animals in regards to blood counts, cell phenotypes and serum chemistry of a specific-pathogen-monitored breeding colony, to facilitate scientific insight into this important and widespread rodent species.

摘要

实验室控制的多乳鼠()生理数据很少,尽管该物种是已知的人畜共患病病毒的储存宿主和载体,包括高致病性拉萨病毒以及其他沙粒病毒和许多种细菌。出于这个原因,多乳鼠是在实验室环境中研究宿主-病毒相互作用的重要啮齿动物。本文提供了特定病原体监测的饲养群中按年龄和性别分布的动物的基本血液参数,包括血液计数、细胞表型和血清化学,以促进对这种重要且广泛分布的啮齿动物物种的科学了解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28d6/7910822/df6a9dc7d170/viruses-13-00187-g001.jpg

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