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加利福尼亚州一项基于人群的研究:早产儿在 1 岁内结局的种族和民族差异。

Racial and ethnic disparities in outcomes through 1 year of life in infants born prematurely: a population based study in California.

机构信息

Department of Pediatrics, University of California San Francisco, San Francisco, CA, USA.

California Preterm Birth Initiative, San Francisco, CA, USA.

出版信息

J Perinatol. 2021 Feb;41(2):220-231. doi: 10.1038/s41372-021-00919-9. Epub 2021 Jan 30.

Abstract

OBJECTIVES

To investigate racial/ethnic differences in rehospitalization and mortality rates among premature infants over the first year of life.

STUDY DESIGN

A retrospective cohort study of infants born in California from 2011 to 2017 (n = 3,448,707) abstracted from a California Office of Statewide Health Planning and Development database. Unadjusted Kaplan-Meier tables and logistic regression controlling for health and sociodemographic characteristics were used to predict outcomes by race/ethnicity.

RESULTS

Compared to White infants, Hispanic and Black early preterm infants were more likely to be readmitted; Black late/moderate preterm (LMPT) infants were more likely to be readmitted and to die after discharge; Hispanic and Black early preterm infants with BPD were more likely to be readmitted; Black LMPT infants with RDS were more likely to be readmitted and die after discharge.

CONCLUSIONS

Racial/ethnic disparities in readmission and mortality rates exist for premature infants across several co-morbidities. Future studies are needed to improve equitability of outcomes.

摘要

目的

调查早产儿在生命的第一年中再入院率和死亡率的种族/民族差异。

研究设计

这是一项回顾性队列研究,对 2011 年至 2017 年期间在加利福尼亚出生的婴儿(n=3,448,707)进行了研究,数据来自加利福尼亚州卫生规划与发展办公室数据库。使用未经调整的 Kaplan-Meier 表和控制健康和社会人口统计学特征的逻辑回归来预测不同种族/民族的结果。

结果

与白人婴儿相比,西班牙裔和黑人早期早产儿更有可能再次入院;黑人晚期/中度早产儿(LMPT)婴儿更有可能再次入院并在出院后死亡;患有 BPD 的西班牙裔和黑人早期早产儿更有可能再次入院;患有 RDS 的黑人 LMPT 婴儿更有可能再次入院并在出院后死亡。

结论

患有多种合并症的早产儿在再入院率和死亡率方面存在种族/民族差异。需要进一步研究以提高结果的公平性。

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