Taylor N E, Schwartz H I
Department of Psychiatry, Beth Israel Medical Center, New York, New York 10003.
J Nerv Ment Dis. 1988 Apr;176(4):249-51. doi: 10.1097/00005053-198804000-00010.
The case of a patient who developed the neuroleptic malignant syndrome following an overdose of amoxapine is presented. It is suggested that amoxapine, an antidepressant structurally related to the neuroleptic loxapine, be added to the list of medications that can cause this potentially lethal syndrome. This case illustrates the need for careful evaluation and attention to differential diagnosis when psychiatric patients develop physical signs and symptoms.
本文介绍了一例因过量服用阿莫沙平而发生抗精神病药恶性综合征的患者病例。有结构上与抗精神病药物洛沙平相关的抗抑郁药阿莫沙平，建议将其列入可导致这种潜在致命综合征的药物清单中。该病例表明，当精神病患者出现身体体征和症状时，需要进行仔细评估并注意鉴别诊断。
