Lab of Applied Biocatalysis, School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, Guangdong, China.
Lab of Applied Biocatalysis, School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, Guangdong, China.
Biotechnol Adv. 2021 Nov 1;51:107702. doi: 10.1016/j.biotechadv.2021.107702. Epub 2021 Jan 27.
Biocatalysis has found enormous applications in sorts of fields as an alternative to chemical catalysis. In the pursue of green and sustainable chemistry, ionic liquids (ILs) have been considered as promising reaction media for biocatalysis, owing to their unique characteristics, such as nonvolatility, inflammability and tunable properties as regards polarity and water miscibility behavior, compared to organic solvents. In recent years, great developments have been achieved in respects to biocatalysis in ILs, especially for preparing various chemicals. This review tends to give illustrative examples with a focus on representative chemicals production by biocatalyst in ILs and elucidate the possible mechanism in such systems. It also discusses how to regulate the catalytic efficiency from several aspects and finally provides an outlook on the opportunities to broaden biocatalysis in ILs.
生物催化作为化学催化的替代方法，在各个领域都得到了广泛的应用。在追求绿色可持续化学的过程中，离子液体 (ILs) 因其独特的性质，如非挥发性、不燃性和可调节的极性和水混溶性等，被认为是生物催化有前途的反应介质。近年来，在 ILs 中的生物催化方面取得了巨大的发展，特别是在制备各种化学品方面。本文综述了生物催化剂在 ILs 中制备各种化学品的代表性实例，并阐明了此类体系中的可能机制。还讨论了如何从几个方面调节催化效率，最后展望了在 ILs 中扩大生物催化的机会。
