白斑病患者门诊喉部活检的诊断率；一项文献综述的病例研究
Diagnostic Yield of Office-Based Laryngeal Biopsy in Patients With Leukoplakia; A Case Study With Review of the Literature.
作者信息
Hamdan Abdul-Latif, Ghanem Anthony, Natout Tamer El, Khalifee Elie
机构信息
Department of Otorhinolaryngology Head and Neck Surgery, American University of Beirut Medical Center, Beirut, Lebanon.
Department of Otorhinolaryngology Head and Neck Surgery, American University of Beirut Medical Center, Beirut, Lebanon.
出版信息
J Voice. 2023 Mar;37(2):282-286. doi: 10.1016/j.jvoice.2020.11.026. Epub 2021 Jan 28.
OBJECTIVE
To review the authors experience in un-sedated office-based biopsies of patients with vocal fold leukoplakia and to review the literature.
MATERIAL AND METHOD
A retrospective review of 29 patients was conducted.
RESULTS
A total of 41 office-based procedures were performed (eight patients had bilateral vocal fold lesions and four patients had the procedure performed twice). In 26 out of the 41 biopsies, the pathology revealed benign lesion. In eight cases, the pathology showed dysplasia (four high-grade and four low-grade). Seven biopsies revealed squamous cell carcinoma. Five patients underwent suspension micro-laryngoscopy for definitive diagnosis. Four of whom had a change in their diagnosis.
CONCLUSION
Un-sedated office-based biopsy of vocal fold leukoplakia is an alternative to suspension microlaryngoscopy in case of carcinoma or nonmalignant lesions.
目的
回顾作者在声带白斑患者非镇静状态下门诊活检的经验并复习相关文献。
材料与方法
对29例患者进行回顾性研究。
结果
共进行了41次门诊手术（8例患者双侧声带病变，4例患者接受了两次手术）。41次活检中有26次病理显示为良性病变。8例病理显示发育异常（4例高级别和4例低级别）。7次活检显示为鳞状细胞癌。5例患者接受了悬吊式显微喉镜检查以明确诊断。其中4例诊断有变化。
结论
对于声带白斑，在诊断为癌或非恶性病变时，非镇静状态下门诊活检是悬吊式显微喉镜检查的一种替代方法。
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