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薰衣草和柑橘对意识重症监护病房患者疼痛的影响:一项平行随机安慰剂对照试验。

Effects of lavender and Citrus aurantium on pain of conscious intensive care unit patients: A parallel randomized placebo-controlled trial.

机构信息

Department of Critical Care Nursing, Razi Faculty of Nursing and Midwifery, Kerman University of Medical Sciences, Kerman 7616913555, Iran.

Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman 7616913555, Iran.

出版信息

J Integr Med. 2021 Jul;19(4):333-339. doi: 10.1016/j.joim.2021.01.006. Epub 2021 Jan 14.

DOI:10.1016/j.joim.2021.01.006
PMID:33516726
Abstract

BACKGROUND

Conscious patients admitted to intensive care units (ICUs) suffer from pain for various reasons, which can affect their recovery process.

OBJECTIVE

The present study compared the effects of aromatherapy with Citrus aurantium and lavender essential oils against placebo for reducing pain in conscious intensive care patients.

DESIGN, SETTING, PARTICIPANTS AND INTERVENTIONS: This study was a parallel randomized placebo-controlled trial. The ICUs of two educational hospitals in Kerman in Southeastern Iran were the study setting. One hundred and fifty conscious intensive care patients were randomly divided into three groups using a stratified block randomization method. Two groups received aromatherapy with essential oils: one with lavender and the other with C. aurantium; these patients received a 30-minute therapy session using their assigned essential oil on the second day of their intensive care stay. The placebo group used 5 drops of normal saline instead of essential oil during their session.

MAIN OUTCOME MEASURES

Patient's pain was assessed using a visual analog scale before the aromatherapy intervention, as well as immediately after and one and three hours after intervention.

RESULTS

The mean pain score of the lavender group was 40.01 before the aromatherapy intervention and fell to 39.40, 30.60 and 23.68 immediately after the intervention, and at hour one and three post-intervention, respectively. The mean pain score of the C. aurantium group was 45.48 before the intervention and was reduced to 32.34 at three hours after the intervention. The mean pain of the placebo group decreased from 42.80 before the intervention to 35.20 at three hours after the intervention. Pain scores of all groups decreased during the study (P < 0.001). The mean pain of the lavender group was significantly lower than that of the placebo group at three hours after the intervention.

CONCLUSION

The results of this study showed that aromatherapy with lavender essential oil reduced pain in conscious ICU patients. Our data could not justify the use of C. aurantium for reducing pain in this population.

TRIAL REGISTRATION

No. IRCT20170116031972N9 (https://en.irct.ir/trial/40827).

摘要

背景

因各种原因,入住重症监护病房(ICU)的清醒患者会感到疼痛,这可能会影响他们的康复过程。

目的

本研究比较了橙花和薰衣草精油芳香疗法与安慰剂对减轻清醒 ICU 患者疼痛的效果。

设计、地点、参与者和干预措施:这是一项平行随机安慰剂对照试验。研究地点为伊朗东南部克尔曼的两所教学医院的 ICU。采用分层区组随机分组方法,将 150 名清醒 ICU 患者随机分为三组。两组患者接受精油芳香疗法:一组用薰衣草,另一组用橙花;这些患者在入住 ICU 的第二天接受 30 分钟的治疗。对照组在治疗期间使用 5 滴生理盐水代替精油。

主要观察指标

在接受芳香疗法干预前、干预即刻、干预后 1 小时和 3 小时,使用视觉模拟评分法评估患者的疼痛程度。

结果

薰衣草组在接受芳香疗法干预前的平均疼痛评分为 40.01,干预后立即降至 39.40、30.60 和 23.68,干预后 1 小时和 3 小时分别降至 39.40、30.60 和 23.68。橙花组在干预前的平均疼痛评分为 45.48,干预后 3 小时降至 32.34。安慰剂组的平均疼痛评分从干预前的 42.80降至干预后 3 小时的 35.20。所有组在研究过程中疼痛评分均降低(P<0.001)。干预后 3 小时,薰衣草组的平均疼痛评分明显低于安慰剂组。

结论

本研究结果表明,薰衣草精油芳香疗法可减轻清醒 ICU 患者的疼痛。我们的数据不能证明橙花可用于减轻该人群的疼痛。

试验注册

IRCT20170116031972N9(https://en.irct.ir/trial/40827)。

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