囊性纤维化患者贾第虫病的患病率。

Prevalence of giardiasis in patients with cystic fibrosis.

作者信息

Roberts D M, Craft J C, Mather F J, Davis S H, Wright J A

机构信息

Department of Pediatrics, School of Medicine, Tulane University, New Orleans, LA 70112.

出版信息

J Pediatr. 1988 Apr;112(4):555-9. doi: 10.1016/s0022-3476(88)80166-5.

DOI:10.1016/s0022-3476(88)80166-5

PMID:3351678

Abstract

A group of 107 patients with cystic fibrosis and a control group of 64 normal members of households of patients with cystic fibrosis were surveyed for Giardia lamblia cysts and trophozoites by counterimmunoelectrophoresis of fecal samples. The patient group had a significantly higher rate of infestation than the control group (28.0% vs 6.3%, P = 0.0006), and the disparity between the two groups increased with age (P = 0.005). Aside from cystic fibrosis, all risk factors examined were without influence, except for the presence of household members less than or equal to 5 years of age. We conclude that our patients with cystic fibrosis have a previously unrecognized increased prevalence of giardiasis compared with that in a control population.

摘要

通过对粪便样本进行对流免疫电泳，对107名囊性纤维化患者及64名囊性纤维化患者家庭中的正常成员组成的对照组进行了贾第鞭毛虫囊肿和滋养体的调查。患者组的感染率显著高于对照组（28.0%对6.3%，P = 0.0006），且两组之间的差距随年龄增长而增大（P = 0.005）。除囊性纤维化外，所检查的所有危险因素均无影响，但存在年龄小于或等于5岁的家庭成员除外。我们得出结论，与对照人群相比，我们的囊性纤维化患者贾第虫病的患病率以前未被认识到有所增加。