Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts.
Division of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts.
Facial Plast Surg. 2021 Aug;37(4):439-445. doi: 10.1055/s-0041-1722894. Epub 2021 Jan 31.
Necrotizing fasciitis (NF) is part of the class of necrotizing soft tissue infections characterized by rapid fascial spread and necrosis of the skin, subcutaneous tissue, and superficial fascia. If left untreated, NF can rapidly deteriorate into multiorgan shock and systemic failure. NF most commonly infects the trunk and lower extremities, although it can sometimes present in the head and neck region. This review provides an overview of NF as it relates specifically to the head and neck region, including its associated clinical features and options for treatment. Noma, a related but relatively unknown disease, is then described along with its relationship with severe poverty.
坏死性筋膜炎（NF）属于坏死性软组织感染的一类，其特征为筋膜迅速扩散和皮肤、皮下组织及浅筋膜坏死。如果不加以治疗，NF 可能迅速恶化为多器官休克和全身性衰竭。NF 最常感染躯干和下肢，尽管有时也会出现在头部和颈部区域。本综述专门针对头部和颈部区域的 NF 进行概述，包括其相关的临床特征和治疗选择。随后还描述了一种相关但鲜为人知的疾病——坏疽性口炎（noma）及其与严重贫困的关系。
