Animal Nutrition and Health, DSM Nutritional Products 4303, Kaiseraugst, Switzerland.
DSM Nutritional Products, Animal Nutrition Research Center, Bazhou, Hebei 065799, P.R. China.
Poult Sci. 2021 Feb;100(2):993-997. doi: 10.1016/j.psj.2020.11.009. Epub 2020 Nov 17.
A total of 480 male Cobb 500 broiler chicks were assigned to one of 6 dietary treatments to explore the energy equivalence of myo-inositol compared with dextrose. The 6 dietary treatments included a corn and soy-based control ration formulated with 5% anhydrous dextrose and 5 further diets that were generated by the sequential displacement of increments of 1% dextrose with myo-inositol. Each diet was fed to 8 replicate cages of 10 chicks per cage from day 8 to day 18 after hatch. The BW gain, feed intake, and feed conversion ratio (FCR) were measured, and on day 15 to day 17, excreta were collected to estimate the total tract nutrient retention. Ileal digestibility of nutrients and tibia mineral content was assessed on day 18. The displacement of dextrose with myo-inositol generated a significant linear reduction in the FCR that did not reach a plateau at 5% dietary inclusion of myo-inositol. There was no effect of the displacement of dextrose with myo-inositol on bone mineral concentration. However, supplemental myo-inositol linearly reduced ileal digestibility of DM, calcium, and ileal digestible energy. Myo-inositol addition resulted in a significant linear increase in the total tract retention of CP. It can be concluded that myo-inositol has an energy equivalence equal to approximately 78% of that of dextrose for young broiler chicks but exerts a range of extra caloric effects that improve feed efficiency and may influence nitrogen (N) retention and the uric acid cycle. Future work should focus on the role of phytase and myo-inositol on uric acid, creatine kinase, and other metabolites involved in renal function and biochemical flows of N in urine and feces in nonruminants.
总共 480 只雄性 Cobb 500 肉鸡小鸡被分配到 6 种不同的饮食处理中，以探索肌醇与葡萄糖的能量等效性。这 6 种饮食处理包括一种基于玉米和大豆的对照饲料，其中含有 5%无水葡萄糖，以及另外 5 种饮食，通过依次用肌醇替代 1%葡萄糖的增量来生成。从孵化后第 8 天到第 18 天，每种饮食分别喂食 8 个重复笼，每个笼中装有 10 只小鸡。测量体重增加、饲料摄入量和饲料转化率（FCR），并在第 15 天到第 17 天收集粪便以估计全肠道养分保留率。第 18 天评估回肠养分消化率和胫骨矿物质含量。用肌醇替代葡萄糖会导致 FCR 呈显著线性降低，但在 5%的肌醇饮食添加量下并未达到平台。用肌醇替代葡萄糖对骨骼矿物质浓度没有影响。然而，补充肌醇会线性降低 DM、钙和回肠可消化能量的回肠消化率。肌醇添加会导致 CP 的全肠道保留率呈显著线性增加。可以得出结论，肌醇对幼肉鸡的能量等效值约为葡萄糖的 78%，但会产生一系列额外的热量效应，从而提高饲料效率，并可能影响氮（N）保留和尿酸循环。未来的工作应重点研究植酸酶和肌醇对尿酸、肌酸激酶和其他与肾功能以及尿液和粪便中 N 的生化流有关的代谢物的作用。
