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髋部骨折患者急性处理的 15 年变化:1 年死亡率呼吁改进。

Fifteen years change in acute management of hip fracture patients: 1-year mortality calls for improvements.

机构信息

UOC Ortopedia e Traumatologia, Ospedale Bolognini Seriate ASST-Bergamo Est, Italia, Via Paderno 21 - 24065 Seriate (BG), Italy.

UOC Ortopedia e Traumatologia, Ospedale Bolognini Seriate ASST-Bergamo Est, Italia, Via Paderno 21 - 24065 Seriate (BG), Italy.

出版信息

Injury. 2021 Aug;52(8):2367-2372. doi: 10.1016/j.injury.2021.01.025. Epub 2021 Jan 20.

Abstract

INTRODUCTION

Over the past two decades, the average age of hip fractured patients has increased, patients are increasingly fragile and their management is more complex. Most of the literature suggest that care improvement lowered short-term mortality but there is no clear evidence whether mid- and long-term mortality rates are improving. The aim of this study was to evaluate the variations in comorbidities in hip fractured patients over 15 years, the changes in mortality and identify the predictive factors for mortality for identifying the patients at higher risk.

MATERIALS AND METHODS

Hip fractured patients admitted in hospital in 2000-2001 (192 patients) and 2015-2016 (323 patients) were retrospectively reviewed. Demographic, clinical and management data from the two cohorts were compared. Thirty-day and 1-year mortality were calculated and compare between the two cohorts. A multivariate logistic regression model were performed to identify the most significant predictors of mortality.

RESULTS

After fifteen years, mean age of hip fracture patients increased by 2.6 years with a 31% increase in comorbidity. The most prevalent comorbidities were hypertension, COPD, diabetes, arrhythmia, renal impairment and dementia. In the 2015-2016 cohort, the age-adjusted mortality at 30 days significantly declined compared to the 2000-2001 cohort (respectively 6.9% vs. 12.5%) but the age-adjusted mortality at 1-year was equivalent. Older age, reduced mobility, higher comorbidity, lateral fractures and male sex were significant risk factors for reduced survival time CONCLUSIONS: After 15 years, there was a significant improvement in 30-days mortality in hip fractured patients despite their increase in comorbidities but this advantage was not observed in 1-year mortality. This suggests the need to implement targeted and longer-term care support for males, older patients and those with greater comorbidities which are at higher risk.

摘要

简介

在过去的二十年中,髋部骨折患者的平均年龄增加,患者越来越脆弱,其管理也更加复杂。大多数文献表明,护理的改善降低了短期死亡率,但尚无明确证据表明中、长期死亡率是否在提高。本研究旨在评估 15 年来髋部骨折患者合并症的变化、死亡率的变化,并确定死亡率的预测因素,以确定高风险患者。

材料和方法

回顾性分析 2000-2001 年(192 例)和 2015-2016 年(323 例)住院髋部骨折患者。比较两组患者的人口统计学、临床和管理数据。计算两组患者的 30 天和 1 年死亡率,并进行比较。采用多变量 logistic 回归模型确定死亡率的最显著预测因素。

结果

15 年后,髋部骨折患者的平均年龄增加了 2.6 岁,合并症增加了 31%。最常见的合并症是高血压、COPD、糖尿病、心律失常、肾功能不全和痴呆。在 2015-2016 年组中,调整年龄后 30 天死亡率与 2000-2001 年组相比显著下降(分别为 6.9%和 12.5%),但调整年龄后 1 年死亡率相当。年龄较大、活动能力下降、合并症较多、外侧骨折和男性是生存时间缩短的显著危险因素。

结论

15 年后,髋部骨折患者 30 天死亡率显著改善,尽管合并症增加,但 1 年死亡率无改善。这表明需要为男性、老年患者和合并症较多的患者提供有针对性的、长期的护理支持,这些患者的风险更高。

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