Department of General Surgery, Royal Perth Hospital, Wellington Street, Perth, WA, 6000, Australia.
School of Surgery, University of Western Australia, Perth, WA, Australia.
World J Surg. 2022 Mar;46(3):512-523. doi: 10.1007/s00268-021-06385-w. Epub 2021 Nov 26.
Emergency laparotomies (EL) are associated with significant morbidity and mortality. To date, 30-day mortality has been predominately reported, and been the focus of various national emergency laparotomy audits. Only a few studies have reported on the long-term mortality associated with EL. The aim of this study was to review the one-year mortality following EL.
A systematic review was conducted using PRISMA guidelines to identify studies published in the last 10 years reporting on long-term mortality associated with EL. The data abstracted included: patient demographics, pathology or type of operation performed for EL, post-operative mortality at 7-day, 30-day, 90-day, 1-year, beyond 1-year and inpatient, functional outcomes and risk factors associated with mortality. A quality assessment of included studies was performed.
Fifteen studies reporting long-term outcomes associated with EL were identified, including the results of 48,023 patients. The indications and/or pathologies for ELs varied. The 30-day mortality after EL ranged from 5.3% to 21.8%, and the one-year mortality ranged from 15.1 to 47%. The mortality in the six studies focusing on elderly patients ranged from 30 to 47%.
The long-term mortality rate associated with EL is substantial. Further study is required to understand the 1-year mortality described in the studies and translate these findings for meaningful application into the clinical care of these patients.
急诊剖腹手术(EL)与较高的发病率和死亡率相关。迄今为止,主要报告了 30 天死亡率,并且一直是各种国家急诊剖腹手术审核的重点。只有少数研究报告了与 EL 相关的长期死亡率。本研究旨在回顾 EL 后的一年死亡率。
采用 PRISMA 指南进行系统评价,以确定过去 10 年中报道与 EL 相关的长期死亡率的研究。提取的数据包括:患者人口统计学、EL 进行的病理或手术类型、术后 7 天、30 天、90 天、1 年、1 年以上和住院患者的死亡率、功能结果以及与死亡率相关的风险因素。对纳入研究进行了质量评估。
确定了 15 项与 EL 相关的长期结果研究,其中包括 48023 例患者的结果。EL 的适应证和/或病理类型各不相同。EL 后的 30 天死亡率范围为 5.3%至 21.8%,1 年死亡率范围为 15.1%至 47%。专注于老年患者的 6 项研究的死亡率范围为 30%至 47%。
EL 相关的长期死亡率相当高。需要进一步研究以了解研究中描述的 1 年死亡率,并将这些发现转化为对这些患者的临床护理有意义的应用。