Zhang Ping, Zhong Weiying, Li Tao, Tan Xianjun, Chen Chao, Li Mingxin, Li Zhonggang, Li Gang, Wang Yunyan
School of Basic Medical Sciences, Shandong University, Jinan, China.
Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine, Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.
Front Neurol. 2021 Jan 13;11:625203. doi: 10.3389/fneur.2020.625203. eCollection 2020.
Despite many therapeutic methods were utilized to treat blood blister-like aneurysms (BBAs), the optimal treatment approach has not yet been defined. This study presents the single center experience with BBAs treated with flow diverter-assisted coiling using semi-deploying technique, and discusses the efficacy and safety of the method. The patients with subarachnoid hemorrhages (SAH) due to BBAs and treated with Pipeline Flex Embolization Device (PED) between November 2015 and February 2019 in our hospital were retrospectively reviewed. Patient demographic data, timing of treatment, angiographic details, treatment techniques, clinical outcomes and follow-up results were recorded. Ten cases (6 women and 4 men) were enrolled. The mean age of patients was 50.7 years (range 40-61 years). The aneurysm size ranged from 2 × 1.7 mm to 4.5 × 3.8 mm. Seven patients were treated with PED assisted coil embolization using semi-deploying technique, and all of the aneurysms were totally obliterated at the follow up. One patient treated with PED assisted coil embolization suffered from parenchymal hemorrhage 3 days after the treatment, and another one patient also treated with PED and coil died of severe vasospasm 10 days after the treatment. There was no reruptured cases during the follow-up. Here we showed that PED assisted coil embolization using semi-deploying technique could be a technically safe and effective treatment for BBAs.
尽管采用了多种治疗方法来治疗血泡样动脉瘤（BBAs），但最佳治疗方法尚未明确。本研究介绍了使用半释放技术的血流导向辅助弹簧圈栓塞治疗BBAs的单中心经验，并讨论了该方法的有效性和安全性。回顾性分析了2015年11月至2019年2月在我院因BBAs导致蛛网膜下腔出血（SAH）并接受Pipeline Flex栓塞装置（PED）治疗的患者。记录患者的人口统计学数据、治疗时间、血管造影细节、治疗技术、临床结果和随访结果。共纳入10例患者（6例女性，4例男性）。患者的平均年龄为50.7岁（范围40 - 61岁）。动脉瘤大小从2×1.7mm到4.5×3.8mm不等。7例患者采用半释放技术的PED辅助弹簧圈栓塞治疗，所有动脉瘤在随访时均完全闭塞。1例接受PED辅助弹簧圈栓塞治疗的患者在治疗后3天发生实质内出血，另1例同样接受PED和弹簧圈治疗的患者在治疗后10天死于严重血管痉挛。随访期间无再破裂病例。我们在此表明，使用半释放技术的PED辅助弹簧圈栓塞可能是一种技术上安全有效的BBAs治疗方法。
