Numasawa Yohei, Yokokura Souichi, Maeda Takashi, Daigo Kyohei, Sakata Shingo, Hashimoto Ryota, Taruoka Akira, Sato Kazuki, Haginiwa Sho, Kojima Hidenori, Tanaka Makoto
Department of Cardiology, Japanese Red Cross Ashikaga Hospital, Ashikaga, Japan.
J Cardiol Cases. 2020 Oct 10;23(2):61-64. doi: 10.1016/j.jccase.2020.09.009. eCollection 2021 Feb.
Spontaneous coronary artery dissection (SCAD) is the most important cause of acute coronary syndrome in pregnant women. Pregnancy-associated SCAD frequently occurs in the third trimester or postpartum period. However, little is known regarding the relationship between the occurrence of SCAD and stillbirth. We describe here a 41-year-old woman complicated by sudden cardiac arrest owing to SCAD in the distal segment of the right coronary artery 13 days after stillbirth. After contacting emergency medical services, she was resuscitated by an automated external defibrillator because the initial electrocardiographic waveform was ventricular fibrillation. After cardiopulmonary resuscitation, the diagnosis of SCAD was confirmed by coronary angiography and intracoronary imaging, including intravascular ultrasound and optical coherence tomography. The patient was managed with conservative medical therapy because the culprit lesion was present in the distal segment of the right coronary artery and coronary blood flow was preserved. No major adverse cardiovascular events, including recurrent ventricular arrhythmia, were observed during hospitalization. Our findings indicate that pregnancy-associated SCAD leading to sudden cardiac arrest may occur in the postpartum period, even after stillbirth. Intravascular imaging plays a pivotal role in diagnosing SCAD. < Pregnancy-associated spontaneous coronary artery dissection (SCAD) is a relatively rare but well-known cause of acute coronary syndrome in pregnant or postpartum women. However, whether the risk of pregnancy-associated SCAD in the postpartum period is different between normal birth and stillbirth remains unknown. Pregnancy-associated SCAD leading to sudden cardiac arrest owing to acute myocardial ischemia may occur in postpartum women, regardless of fetal survival.>.
自发性冠状动脉夹层(SCAD)是孕妇急性冠状动脉综合征的最重要病因。妊娠相关的SCAD常发生在妊娠晚期或产后。然而,关于SCAD的发生与死产之间的关系,人们知之甚少。我们在此描述一名41岁女性,在死产13天后因右冠状动脉远端SCAD并发心脏骤停。联系紧急医疗服务后,由于初始心电图波形为心室颤动,她通过自动体外除颤器复苏。心肺复苏后,通过冠状动脉造影和冠状动脉内成像(包括血管内超声和光学相干断层扫描)确诊为SCAD。由于罪犯病变位于右冠状动脉远端且冠状动脉血流得以保留,患者接受了保守药物治疗。住院期间未观察到包括复发性室性心律失常在内的重大不良心血管事件。我们的研究结果表明,妊娠相关的SCAD导致心脏骤停可能发生在产后,甚至在死产后。血管内成像在诊断SCAD中起关键作用。<妊娠相关的自发性冠状动脉夹层(SCAD)是孕妇或产后妇女急性冠状动脉综合征中一种相对罕见但广为人知的病因。然而,产后正常分娩和死产的妊娠相关SCAD风险是否不同仍不清楚。无论胎儿是否存活,产后妇女都可能发生妊娠相关的SCAD导致因急性心肌缺血而心脏骤停。>