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[多发性颌骨棕色瘤的影像学特征:病例报告]

[Imaging features of multiple maxillomandibular brown tumors: a case report].

作者信息

Adnane Asmaa, Merzem Aicha, Harmak Meryem, Belgadir Hasnaa, Amriss Omar, Moussali Naima, Elbenna Naima

机构信息

Département de Radiologie, Faculté de Médecine et de Pharmacie, Université Hassan II Casablanca, Casablanca, Maroc.

出版信息

Pan Afr Med J. 2021 Jan 5;38:4. doi: 10.11604/pamj.2021.38.4.27141. eCollection 2021.

Abstract

Brown tumors are rare osteolytic lesions occurring in 1.5-1.7% of patients with chronic end-stage renal failure. They are caused by PTH-induced bone remodeling. We here report the case of a young woman on hemodialysis for chronic end-stage renal failure with painless maxillo-mandibular swellings occurred 7 months before. Clinical examination showed facial deformity with two maxillary and mandibular masses to palpation. Laboratory tests revealed hypocalcemia, hyperphosphatemia with hyperparathyroidism. CT scan of the face revealed multiple osteolytic masses in the maxillary and mandibular bones, with significant bone rarefaction and signs of diffuse bone resorption. The diagnosis of multiple brown tumors of the face was retained based on clinical, biological and radiological features. Brown tumors are a rare entity usually characterized by maxillomandibular involvement in patients with chronic renal failure. Practitioners should suspect them, hence the interest in this study.

摘要

棕色瘤是一种罕见的溶骨性病变,发生于1.5%-1.7%的慢性终末期肾衰竭患者中。它们由甲状旁腺激素诱导的骨重塑引起。我们在此报告一例年轻女性患者,她因慢性终末期肾衰竭接受血液透析,7个月前出现无痛性上颌-下颌肿胀。临床检查显示面部畸形,触诊可及两个上颌和下颌肿物。实验室检查显示低钙血症、高磷血症伴甲状旁腺功能亢进。面部CT扫描显示上颌骨和下颌骨有多个溶骨性肿物,伴有明显的骨质稀疏和弥漫性骨吸收迹象。根据临床、生物学和放射学特征,确诊为面部多发性棕色瘤。棕色瘤是一种罕见的疾病,通常表现为慢性肾衰竭患者的上颌下颌受累。医生应怀疑此病,因此本研究具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6db6/7825377/d8b199751727/PAMJ-38-4-g001.jpg

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