Antonelli John R, Hottel Timothy L
Department of Prosthodontics, Nova Southeastern University, Health Professions Division, College of Dental Medicine, 3200 South University Drive, Fort Lauderdale, FL 33328-2018, USA.
Spec Care Dentist. 2003;23(1):28-34. doi: 10.1111/j.1754-4505.2003.tb00286.x.
Renal osteodystrophy, characterized by uneven bone growth and demineralization, is described. Oral manifestations of the disorder are described, and the value of dental radiographs in early detection of renal osteodystrophy is noted. A case report of a patient with severe oral complications, which resulted from long-standing end-stage renal disease and secondary hyperparathyroidism, is presented. Giant cell lesions of hyperparathyroidism, referred to as brown tumors (which may be associated with pain and swelling), are the key clinical oral manifestations and are the most dramatic dental radiographic finding in patients with renal osteodystrophy. Bone changes may include loss of lamina dura, giant cell lesions of hyperparathyroidism, and bone demineralization. The dentist's role in detection, assessment, and treatment is stressed.
本文描述了以骨生长不均和脱矿质为特征的肾性骨营养不良。文中阐述了该病症的口腔表现，并指出牙科X光片在早期检测肾性骨营养不良中的价值。本文还呈现了一例因长期终末期肾病和继发性甲状旁腺功能亢进导致严重口腔并发症患者的病例报告。甲状旁腺功能亢进的巨细胞病变，即所谓的棕色瘤（可能伴有疼痛和肿胀），是主要的临床口腔表现，也是肾性骨营养不良患者最显著的牙科X光表现。骨质变化可能包括硬骨板丧失、甲状旁腺功能亢进的巨细胞病变和骨质脱矿质。文中强调了牙医在检测、评估和治疗中的作用。
