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一名患有多种合并症的疗养院患者的耳念珠菌尿路感染

Candida Auris Urinary Tract Infection in a Nursing Home Patient With Multicomorbidities.

作者信息

Garcia Rivera Mirian V, Heyl Jonathan J, Oh Michael C

机构信息

Internal Medicine, St. John's Episcopal Hospital, New York, USA.

Internal Medicine, Lake Erie College of Osteopathic Medicine (LECOM), Bradenton, USA.

出版信息

Cureus. 2020 Dec 27;12(12):e12322. doi: 10.7759/cureus.12322.

Abstract

Candida (C.) auris is an opportunistic ascomycetous budding yeast that has been emerging as an invasive, multidrug-resistant pathogen over the past 11 years since its discovery. Candida auris infection has raised considerable attention in public health organizations due to its rising number of cases, virulence, and unique resistance to commonly used mycofungal therapy. This case follows a 64-year-old male with multiple comorbidities from the nursing home presenting with polybacterial sepsis along with a urinary tract infection growing Candida auris. Along with treatment for sepsis, the patient was placed on the Centers for Disease Control and Prevention's (CDC's) recommended regimen of micafungin to eradicate C. auris infection and isolation precautions. Cases should be approached carefully and reported to public agencies such as the CDC and state health department.

摘要

耳念珠菌是一种机会性子囊芽殖酵母,自发现以来的11年里,它已成为一种侵袭性、多重耐药病原体。由于耳念珠菌感染病例不断增加、毒力强以及对常用抗真菌治疗具有独特耐药性,其感染已引起公共卫生组织的高度关注。该病例为一名来自养老院的64岁男性,患有多种合并症,出现多菌性败血症以及耳部念珠菌尿路感染。在对败血症进行治疗的同时,患者接受了美国疾病控制与预防中心(CDC)推荐的米卡芬净治疗方案,以根除耳念珠菌感染并采取隔离预防措施。应对此类病例进行谨慎处理,并向CDC和州卫生部门等公共机构报告。

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本文引用的文献

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Multidrug-resistant endemic clonal strain of Candida auris in India.印度耳念珠菌的多药耐药地方性克隆菌株。
Eur J Clin Microbiol Infect Dis. 2014 Jun;33(6):919-26. doi: 10.1007/s10096-013-2027-1. Epub 2013 Dec 20.
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Lipolytic enzymes involved in the virulence of human pathogenic fungi.参与人类致病真菌毒力的脂解酶。
Mycobiology. 2013 Jun;41(2):67-72. doi: 10.5941/MYCO.2013.41.2.67. Epub 2013 Jun 30.

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