Singh Peetam, Pandey Anita
Department of Microbiology, Subharti Medical College, Meerut, Uttar Pradesh, India.
Curr Med Mycol. 2024 Mar 1;10. doi: 10.22034/cmm.2024.345249.1558. eCollection 2024.
An increasing number of invasive infections due to multidrug-resistant species have been reported worldwide. Among these species, has attracted more attention in recent years due to major outbreaks in healthcare facilities globally and is considered an emerging pathogen. This study was planned to observe the occurrence of infections in a tertiary care hospital in India.
The clinical specimens were inoculated on Sabouraud dextrose agar along with other conventional culture media for aerobic culture based on specimen type. The blood culture was performed by BacT/ALERT 3D automated blood culture system. After preliminary identification, the species-level identification of was performed by the VITEK-2 compact automated system from bioMerieux, France.
Out of a total of 497 isolates, 21.33% were , while 78.67% were non- species. comprised 3.22% of all isolates. Among various risk factors, intensive care unit stay was the most common risk factor associated with infection. The antifungal susceptibility data highlighted the resistance of against most of the antifungals except echinocandins.
Infections due to are emerging in hospital environments, especially among individuals having various risk factors. The resistant nature of further complicates the situation leading to frequent antifungal treatment failure.
全球范围内报告的耐多药菌种引起的侵袭性感染数量不断增加。在这些菌种中,近年来由于全球医疗机构中的重大疫情爆发而受到更多关注,并被视为一种新兴病原体。本研究旨在观察印度一家三级护理医院中[菌种名称]感染的发生情况。
根据标本类型,将临床标本接种在沙氏葡萄糖琼脂以及其他用于需氧培养的传统培养基上。采用BacT/ALERT 3D自动血培养系统进行血培养。初步鉴定后,使用法国生物梅里埃公司的VITEK-2 compact自动系统对[菌种名称]进行菌种水平鉴定。
在总共497株[菌种名称]分离株中,21.33%为[目标菌种名称],而78.67%为非[目标菌种名称]菌种。[目标菌种名称]占所有[菌种名称]分离株的3.22%。在各种危险因素中,入住重症监护病房是与[目标菌种名称]感染相关的最常见危险因素。抗真菌药敏数据突出显示,除棘白菌素外,[目标菌种名称]对大多数抗真菌药物耐药。
[目标菌种名称]感染在医院环境中正在出现,尤其是在具有各种危险因素的个体中。[目标菌种名称]的耐药性使情况进一步复杂化,导致抗真菌治疗频繁失败。