Wesolow Jacqueline T
Internal Medicine, Moffitt Cancer Center, Tampa, USA.
Cureus. 2020 Dec 28;12(12):e12343. doi: 10.7759/cureus.12343.
Pyoderma gangrenosum is a rare inflammatory skin disease usually associated with an underlying internal condition. Diseases most commonly linked with pyoderma gangrenosum are inflammatory bowel disease (ulcerative colitis and Crohn's disease), rheumatoid arthritis, and hematologic malignancies such as leukemia and lymphoma. In rare instances, it can occur as a type of paraneoplastic syndrome in patients with cancer. The most common cancers associated with pyoderma gangrenosum are breast cancer followed by rectal, gastric, renal, and lung cancers. There are scarce reports of neuroendocrine tumors associated with pyoderma gangrenosum. We discuss a case of a pancreatic neuroendocrine cancer patient afflicted with pyoderma gangrenosum.
坏疽性脓皮病是一种罕见的炎症性皮肤病，通常与潜在的内科疾病有关。与坏疽性脓皮病最常相关的疾病是炎症性肠病（溃疡性结肠炎和克罗恩病）、类风湿性关节炎以及血液系统恶性肿瘤，如白血病和淋巴瘤。在罕见情况下，它可作为癌症患者的一种副肿瘤综合征出现。与坏疽性脓皮病相关的最常见癌症是乳腺癌，其次是直肠癌、胃癌、肾癌和肺癌。关于与坏疽性脓皮病相关的神经内分泌肿瘤的报道很少。我们讨论一例患有坏疽性脓皮病的胰腺神经内分泌癌患者的病例。
