输精管吻合术部位肉芽肿形成的影响。

Effects of granuloma formation at site of vasovasostomy.

作者信息

Carey P O, Howards S S, Flickinger C J, Herr J C, Gallien T N, Caloras D, Spell D R

机构信息

Department of Urology, University of Virginia Medical School, Charlottesville.

出版信息

J Urol. 1988 Apr;139(4):853-6. doi: 10.1016/s0022-5347(17)42661-9.

DOI:10.1016/s0022-5347(17)42661-9

PMID:3352060

Abstract

Spermatic granulomas forming after vasectomy reversal have been thought to mechanically compromise the anastomosis. We have studied the physiologic effects of vasectomy and vasovasostomy in rats. Following delayed microsurgical vasovasostomy, fluid flow through the anastomosis and cauda epididymidal hydrostatic pressure are not significantly different in tracts that form, or do not form, sperm granulomas at the anastomosis. Given a properly performed microsurgical vasectomy reversal, a sperm granuloma arising from a small leak does not appear to mechanically compromise the anastomosis in the rat. Fertility after vasovasostomy is not significantly reduced in rats with granulomas.

摘要

输精管复通术后形成的精子肉芽肿被认为会在机械上损害吻合口。我们研究了输精管结扎和输精管吻合术对大鼠的生理影响。在延迟显微外科输精管吻合术后，吻合口处形成或未形成精子肉芽肿的输精管中，通过吻合口的液体流动和附睾尾部的静水压力并无显著差异。在进行得当的显微外科输精管复通术后，由小渗漏产生的精子肉芽肿似乎并不会在机械上损害大鼠的吻合口。有肉芽肿的大鼠输精管吻合术后的生育能力并未显著降低。