一名从巴基斯坦回国的患者身上出现广泛耐药性伤寒杆菌，美罗培南单药治疗后复发并出现并发症。
Extensively drug-resistant Typhi in a patient returning from Pakistan, complicated by relapse with meropenem monotherapy.
作者信息
Caravedo Maria A, Kaura Abhimanyu, Reynoso David
机构信息
Department of Infectious Diseases, University of Texas Medical Branch, Galveston TX, USA.
出版信息
IDCases. 2021 Jan 14;23:e01048. doi: 10.1016/j.idcr.2021.e01048. eCollection 2021.
Abstract
In developing countries, typhoid fever is a common cause of febrile illness accompanied by abdominal pain and weakness. It is caused by Typhi. Humans are the only known reservoir of infection, and typhoid fever is common in regions where access to clean water and sanitation is limited. The antimicrobials of choice for a case of typhoid fever acquired outside Pakistan are third generation cephalosporins. Lately, cases of extensively drug-resistant (XDR) Typhi have been reported in people with a travel history to Pakistan. We present a case of XDR typhoid fever which relapsed after treatment with meropenem.
摘要
在发展中国家，伤寒热是伴有腹痛和虚弱的发热性疾病的常见病因。它由伤寒杆菌引起。人类是已知的唯一感染源，在清洁水和卫生设施供应有限的地区，伤寒热很常见。在巴基斯坦境外感染的伤寒热病例，首选的抗菌药物是第三代头孢菌素。最近，有旅行史到过巴基斯坦的人被报告出现广泛耐药伤寒杆菌病例。我们报告一例广泛耐药伤寒热病例，该病例在接受美罗培南治疗后复发。
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