Gorthi Ramya S, Kamel Ghassan, Dhindsa Sandeep, Nayak Ravi P
Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, Missouri.
Division of Endocrinology, Diabetes and Metabolism, Saint Louis University School of Medicine, Saint Louis, Missouri.
AACE Clin Case Rep. 2021 Jan-Feb;7(1):6-9. doi: 10.1016/j.aace.2020.11.010. Epub 2020 Dec 28.
Diabetes mellitus has been recognized as one of the comorbidities that predict the severity of illness in patients infected with COVID-19. The characteristics of patients presenting with diabetic ketoacidosis (DKA) and COVID-19 infection have not been described.
We describe 5 patients with DKA and concomitant COVID-19 admitted to the intensive care unit of an academic medical center. Three patients had type 1 diabetes mellitus, and 2 patients had type 2 diabetes mellitus.
While DKA with an infectious etiology is a common presentation, we observed that the patients with DKA precipitated by COVID-19 presented with atypical symptoms. COVID-19 infection was revealed during search for an etiology of DKA.
It is prudent to have a low threshold to screen for COVID-19 infection in patients with DKA.
糖尿病已被认为是预测新冠病毒病(COVID-19)感染患者疾病严重程度的合并症之一。目前尚未描述糖尿病酮症酸中毒(DKA)合并COVID-19感染患者的特征。
我们描述了5例入住一所学术医疗中心重症监护病房的DKA合并COVID-19感染患者。3例为1型糖尿病患者,2例为2型糖尿病患者。
虽然感染性病因导致的DKA很常见,但我们观察到由COVID-19引发DKA的患者表现出非典型症状。在寻找DKA病因的过程中发现了COVID-19感染。
对DKA患者进行COVID-19感染筛查时保持较低的阈值是谨慎的做法。