严重急性呼吸综合征冠状病毒2的热灭活
Heat inactivation of the severe acute respiratory syndrome coronavirus 2.
作者信息
Batéjat Christophe, Grassin Quentin, Manuguerra Jean-Claude, Leclercq India
机构信息
Institut Pasteur, Unité Environnement et Risques Infectieux, Cellule d'Intervention Biologique d'Urgence (CIBU), 28 rue du Dr. Roux, Paris, France.
Université de Paris, Cellule Pasteur, 28 rue du Dr. Roux F-75015 Paris, France.
出版信息
J Biosaf Biosecur. 2021 Jun;3(1):1-3. doi: 10.1016/j.jobb.2020.12.001. Epub 2021 Jan 23.
Cell culture medium, nasopharyngeal and sera samples spiked with SARS-CoV-2 were subjected to heat inactivation for various periods of time, ranging from 30 s to 60 min. Our results showed that SARS-CoV-2 could be inactivated in less than 30 min, 15 min, and 3 min at 56 °C, 65 °C, and 95 °C, respectively. These data could help laboratory workers to improve their protocols by handling the virus in biosafety conditions.
将含有新冠病毒的细胞培养基、鼻咽样本和血清样本进行不同时长的热灭活处理，时长从30秒到60分钟不等。我们的结果显示，新冠病毒分别在56℃、65℃和95℃下，可在不到30分钟、15分钟和3分钟内被灭活。这些数据有助于实验室工作人员在生物安全条件下处理病毒时改进其操作流程。
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