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脉冲射频治疗阴部神经痛。一项长期随访的病例系列研究。

Pulsed Radiofrequency of Pudendal Nerve for Treatment in Patients with Pudendal Neuralgia. A Case Series with Long-Term Follow-Up.

机构信息

Department of Gynaecology, University Medical Center Utrecht, Utrecht, The Netherlands.

Pain Clinic, Department of Anaesthesiology, University Medical Center Utrecht, Utrecht, The Netherlands.

出版信息

Pain Pract. 2021 Jul;21(6):703-707. doi: 10.1111/papr.12999. Epub 2021 Feb 22.

Abstract

Pudendal neuralgia (PN) is an impairing neuropathic disorder, affecting both men and women, involving a severe burning and sharp pain along the course of the pudendal nerve. Treatment is often insufficient, and options are limited. Pulsed radiofrequency (PRF) is a technique which might be useful in therapy. This case series aims to determine the effectiveness of PRF in patients with PN in the context of evaluation of care. Between 2010 and 2016, all female patients of University Medical Center Utrecht diagnosed with PN who experience insufficient pain relief after common treatment were offered PRF. Patient Global Impression of Improvement (PGI-I) scores were assessed at 3-month follow-up and at long-term follow-up (median 4 years). PGI-I scores were recorded to evaluate our quality of care. Twenty patients with PN consented to undergo PRF. We lost one patient in follow-up. Seventy-nine percent of the patients described their condition as "(very) much better" at 3-month follow-up. At long-term follow-up, 89% of the patients described their condition as "(very) much better." No serious side effects were observed. In conclusion, PRF is a successful treatment option in patients not responding to standard treatment options, including pudendal nerve blocks. PRF of the pudendal nerve can be used for PN to provide relief in patients' chronic pelvic pain.

摘要

阴部神经痛(PN)是一种使人虚弱的神经病变,影响男性和女性,涉及阴部神经沿线上的严重烧灼感和锐痛。治疗往往不足,选择有限。脉冲射频(PRF)是一种可能在治疗中有用的技术。本病例系列旨在评估护理过程中,评估 PRF 在 PN 患者中的疗效。2010 年至 2016 年间,乌得勒支大学医学中心的所有女性 PN 患者在接受常规治疗后疼痛缓解不足,均被提供 PRF。在 3 个月和长期随访(中位数为 4 年)时评估患者整体印象改善(PGI-I)评分,以评估我们的护理质量。20 名 PN 患者同意接受 PRF。随访中我们失去了 1 名患者。79%的患者在 3 个月随访时描述他们的病情“(非常)明显好转”。长期随访时,89%的患者描述他们的病情“(非常)明显好转”。未观察到严重的副作用。总之,PRF 是对标准治疗方案无反应的患者的成功治疗选择,包括阴部神经阻滞。阴部神经 PRF 可用于治疗 PN,为患者的慢性盆腔疼痛提供缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9cc9/8359332/c6e1b1c860f8/PAPR-21-703-g001.jpg

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