National Laboratory for Scientific Computing, Petrópolis, Brazil.
National Institute of Science and Technology in Medicine Assisted by Scientific Computing, Petrópolis, Brazil.
Int J Numer Method Biomed Eng. 2021 May;37(5):e3442. doi: 10.1002/cnm.3442. Epub 2021 Feb 18.
The characterization of vascular geometry is a fundamental step towards the correct interpretation of coronary artery disease. In this work, we report a comprehensive comparison of the geometry featured by coronary vessels as obtained from coronary computed tomography angiography (CCTA) and the combination of intravascular ultrasound (IVUS) with bi-plane angiography (AX) modalities. We analyzed 34 vessels from 28 patients with coronary disease, which were deferred to CCTA and IVUS procedures. We discuss agreement and discrepancies between several geometric indexes extracted from vascular geometries. Such an analysis allows us to understand to which extent the coronary vascular geometry can be reliable in the interpretation of geometric risk factors, and as a surrogate to characterize coronary artery disease.
血管几何结构的描述是正确解释冠状动脉疾病的基本步骤。在这项工作中,我们报告了从冠状动脉计算机断层血管造影(CCTA)和血管内超声(IVUS)与双平面血管造影(AX)相结合的方式中获得的冠状动脉的几何特征的全面比较。我们分析了 28 例患有冠状动脉疾病的患者的 34 支血管,这些患者被推迟进行 CCTA 和 IVUS 检查。我们讨论了从血管几何结构中提取的几个几何指标之间的一致性和差异。这种分析使我们能够了解冠状动脉血管几何结构在解释几何危险因素方面的可靠性程度,并作为特征描述冠状动脉疾病的替代方法。