Syncytia formation by SARS-CoV-2-infected cells.
作者信息
Buchrieser Julian, Dufloo Jérémy, Hubert Mathieu, Monel Blandine, Planas Delphine, Rajah Maaran Michael, Planchais Cyril, Porrot Françoise, Guivel-Benhassine Florence, Van der Werf Sylvie, Casartelli Nicoletta, Mouquet Hugo, Bruel Timothée, Schwartz Olivier
出版信息
EMBO J. 2021 Feb 1;40(3):e107405. doi: 10.15252/embj.2020107405.
Abstract
摘要
相似文献
1
Syncytia formation by SARS-CoV-2-infected cells.严重急性呼吸综合征冠状病毒2（SARS-CoV-2）感染细胞形成合胞体。
EMBO J. 2021 Feb 1;40(3):e107405. doi: 10.15252/embj.2020107405.
2
Recombinant ACE2 Expression Is Required for SARS-CoV-2 To Infect Primary Human Endothelial Cells and Induce Inflammatory and Procoagulative Responses.重组 ACE2 表达是 SARS-CoV-2 感染原代人血管内皮细胞并诱导炎症和促凝反应所必需的。
mBio. 2020 Dec 11;11(6):e03185-20. doi: 10.1128/mBio.03185-20.
3
Re-evaluation of the involvement of the adhesion molecules ICAM-1/LFA-1 in syncytia formation of HIV-1-infected subclones of a CEM T-cell leukemic line.对黏附分子ICAM-1/LFA-1参与CEM T细胞白血病细胞系的HIV-1感染亚克隆的合胞体形成的重新评估。
AIDS Res Hum Retroviruses. 1991 Jan;7(1):45-53. doi: 10.1089/aid.1991.7.45.
4
Syncytia formation during SARS-CoV-2 lung infection: a disastrous unity to eliminate lymphocytes.新型冠状病毒肺炎肺部感染期间的多核巨细胞形成：清除淋巴细胞的灾难性联合。
Cell Death Differ. 2021 Jun;28(6):2019-2021. doi: 10.1038/s41418-021-00795-y. Epub 2021 May 12.
5
HIV-1-Induced Small T Cell Syncytia Can Transfer Virus Particles to Target Cells through Transient Contacts.HIV-1诱导的小T细胞融合体可通过短暂接触将病毒颗粒转移至靶细胞。
Viruses. 2015 Dec 12;7(12):6590-603. doi: 10.3390/v7122959.
6
Maternal, fetal and neonatal outcomes of large series of SARS-CoV-2 positive pregnancies in peripartum period: A single-center prospective comparative study.围产期大量 SARS-CoV-2 阳性妊娠的母婴及新生儿结局：一项单中心前瞻性对照研究。
Eur J Obstet Gynecol Reprod Biol. 2021 Feb;257:11-18. doi: 10.1016/j.ejogrb.2020.11.068. Epub 2020 Dec 1.
7
Lipid droplets fuel SARS-CoV-2 replication and production of inflammatory mediators.脂滴为 SARS-CoV-2 的复制和炎症介质的产生提供燃料。
PLoS Pathog. 2020 Dec 16;16(12):e1009127. doi: 10.1371/journal.ppat.1009127. eCollection 2020 Dec.
8
Identifying Pathways and Networks Associated With the SARS-CoV-2 Cell Receptor ACE2 Based on Gene Expression Profiles in Normal and SARS-CoV-2-Infected Human Tissues.基于正常和感染SARS-CoV-2的人体组织中的基因表达谱，鉴定与SARS-CoV-2细胞受体ACE2相关的信号通路和网络。
Front Mol Biosci. 2020 Oct 16;7:568954. doi: 10.3389/fmolb.2020.568954. eCollection 2020.
9
SARS-CoV-2 viral RNA load dynamics in the nasopharynx of infected children.儿童感染者鼻咽部的 SARS-CoV-2 病毒 RNA 载量动态变化。
Epidemiol Infect. 2021 Jan 11;149:e18. doi: 10.1017/S095026882100008X.
10
National registry for patients with inflammatory rheumatic diseases (IRD) infected with SARS-CoV-2 in Germany (ReCoVery): a valuable mean to gain rapid and reliable knowledge of the clinical course of SARS-CoV-2 infections in patients with IRD.德国炎症性风湿病（IRD）患者感染 SARS-CoV-2 的国家登记处（ReCoVery）：了解 IRD 患者 SARS-CoV-2 感染临床病程的快速可靠知识的宝贵手段。
RMD Open. 2020 Sep;6(2). doi: 10.1136/rmdopen-2020-001332.
引用本文的文献
1
TMEM106B Supports Viral Entry and Syncytia Formation Mediated by the Spike Proteins From Omicron BA.2.86 and JN.1.跨膜蛋白106B（TMEM106B）支持由奥密克戎BA.2.86和JN.1的刺突蛋白介导的病毒进入和多核巨细胞形成。
J Med Virol. 2025 Jul;97(7):e70439. doi: 10.1002/jmv.70439.
2
A novel luciferase-based assay for quantifying coronavirus-induced syncytia.一种基于荧光素酶的新型检测方法，用于定量冠状病毒诱导的合胞体。
Sci Rep. 2025 May 20;15(1):17423. doi: 10.1038/s41598-025-02037-4.
3
Anti-interferon armamentarium of human coronaviruses.人类冠状病毒的抗干扰素手段
Cell Mol Life Sci. 2025 Mar 13;82(1):116. doi: 10.1007/s00018-025-05605-z.
4
Immune-Boosting and Antiviral Effects of Antioxidants in COVID-19 Pneumonia: A Therapeutic Perspective.抗氧化剂在新冠肺炎肺炎中的免疫增强和抗病毒作用：治疗视角
Life (Basel). 2025 Jan 16;15(1):113. doi: 10.3390/life15010113.
5
Facilitating and restraining virus infection using cell-attachable soluble viral receptors.利用细胞附着型可溶性病毒受体促进和抑制病毒感染。
Proc Natl Acad Sci U S A. 2024 Nov 5;121(45):e2414583121. doi: 10.1073/pnas.2414583121. Epub 2024 Oct 31.
6
Unveiling the Pathological Mechanisms of Death Induced by SARS-CoV-2 Viral Pneumonia.揭示严重急性呼吸综合征冠状病毒2型病毒性肺炎所致死亡的病理机制
Microorganisms. 2024 Feb 24;12(3):459. doi: 10.3390/microorganisms12030459.
7
Temperature impacts SARS-CoV-2 spike fusogenicity and evolution.温度影响 SARS-CoV-2 刺突的融合性和进化。
mBio. 2024 Apr 10;15(4):e0336023. doi: 10.1128/mbio.03360-23. Epub 2024 Feb 27.
8
Quercetin inhibits SARS-CoV-2 infection and prevents syncytium formation by cells co-expressing the viral spike protein and human ACE2.槲皮素可抑制新型冠状病毒（SARS-CoV-2）感染，并防止共表达病毒刺突蛋白和人类血管紧张素转换酶2（ACE2）的细胞形成合胞体。
Virol J. 2024 Jan 25;21(1):29. doi: 10.1186/s12985-024-02299-w.
9
Transcriptomic analysis of sorted lung cells revealed a proviral activity of the NF-κB pathway toward SARS-CoV-2.对分选的肺细胞进行转录组分析揭示了NF-κB信号通路对严重急性呼吸综合征冠状病毒2（SARS-CoV-2）的前病毒活性。
iScience. 2023 Nov 13;26(12):108449. doi: 10.1016/j.isci.2023.108449. eCollection 2023 Dec 15.
10
Integrin αβ contributes to cell fusion and inflammation mediated by SARS-CoV-2 spike via RGD-independent interaction.整合素 αβ 通过非 RGD 依赖性相互作用促进 SARS-CoV-2 刺突介导的细胞融合和炎症反应。
Proc Natl Acad Sci U S A. 2023 Dec 12;120(50):e2311913120. doi: 10.1073/pnas.2311913120. Epub 2023 Dec 7.
Zotero 插件