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2009 年至 2018 年向佐治亚中毒中心报告的青少年蓄意疑似自杀中毒暴露情况,并与全国进行比较。

Intentional suspected suicide exposures by poisoning among adolescents from 2009 to 2018 reported to the Georgia Poison Center and compared nationally.

机构信息

Georgia Poison Center, Atlanta, GA, USA.

Department of Emergency Medicine, Emory University, Atlanta, GA, USA.

出版信息

Basic Clin Pharmacol Toxicol. 2021 May;128(5):699-708. doi: 10.1111/bcpt.13563. Epub 2021 Feb 8.

Abstract

This retrospective chart review aimed to report the incidence and characteristics of intentional suspected suicide among 13- to 19-year-olds reported to the Georgia Poison Center (GPC) and compared nationally from 2009 to 2018. Of the 19 733 cases reported to the GPC, 74.9% were females. The total number of cases more than doubled from 2009 to 2018, increasing annually by 10%. Majority (90.1%) of the cases occurred in the home, and 60.4% of the cases resulted in either no effect or minor effect. More than half (66.5%) of the cases involved only one substance. Pharmaceuticals made up 94.5% of the substances used, with analgesics accounting for 42.10% and antidepressants at 20.77%. A significant difference was found in substances used between males and females (P < .001). Females were more likely to use analgesics (45.17% vs 32.90%), and males were more likely to use sedatives/hypnotics/antipsychotics (20.45% vs 13.58%). While the majority of the GPC patients were females, the GPC was more likely to have fewer female patients (74.7% vs 75.7%) and more male patients (25.3% vs 24.3%) than other poison centers. Intentional suspected suicide exposures by poisoning are on the rise and higher among females, demonstrating a need for strengthened intervention and prevention strategies.

摘要

本回顾性图表研究旨在报告向佐治亚州毒物中心(GPC)报告的 13 至 19 岁青少年故意疑似自杀的发生率和特征,并与 2009 年至 2018 年全国数据进行比较。在向 GPC 报告的 19733 例病例中,有 74.9%为女性。病例总数从 2009 年到 2018 年翻了一番多,每年增长 10%。大多数(90.1%)病例发生在家庭中,60.4%的病例没有或只有轻微影响。超过一半(66.5%)的病例涉及一种物质。所使用的物质中有 94.5%是药品,其中镇痛药占 42.10%,抗抑郁药占 20.77%。男性和女性使用的物质之间存在显著差异(P<.001)。女性更可能使用镇痛药(45.17%比 32.90%),而男性更可能使用镇静剂/催眠剂/抗精神病药(20.45%比 13.58%)。尽管 GPC 的大多数患者是女性,但 GPC 更可能有较少的女性患者(74.7%比 75.7%)和更多的男性患者(25.3%比 24.3%),而其他毒物中心则有更多的女性患者。因中毒导致的故意疑似自杀暴露呈上升趋势,且女性中更高,这表明需要加强干预和预防策略。

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