Department of Materials and Mineral Resources Engineering, National Taipei University of Technology, No. 1, Section 3, Chung-Hsiao East Road, Taipei, 106, Taiwan, ROC.
Department of Materials and Mineral Resources Engineering, National Taipei University of Technology, No. 1, Section 3, Chung-Hsiao East Road, Taipei, 106, Taiwan, ROC.
Colloids Surf B Biointerfaces. 2021 Apr;200:111577. doi: 10.1016/j.colsurfb.2021.111577. Epub 2021 Jan 19.
In this work, we report a novel preparation of selenium nanorods (Se) doped cobalt oxide (CoO) nanoflowers encapsulated with graphene oxide (GO) nanocomposite (NC). Se nanorods were successfully decorated on CoO nanoflowers and an increase in electrical conductivity was observed in Se-CoO@GO-NC. The as-prepared Se-CoO@GO-NC was utilized as an effective nanocomposite for the electrochemical detection of dimetridazole (DMZ) for the first time in the field of electrochemical sensors. Se-CoO@GO-NC modified glassy carbon electrode (GCE) which showed an excellent cathodic current response (17.6 μA) at the lower potential at -0.7314 V upon DMZ sensing. With the various optimized conditions, Se-CoO@GO-NC based electrochemical sensor displayed a lengthy linear range of 0.02-83.72 μM, limit of detection 3.4 nM and sensitivity of 1.898 μA.μM. cm for DMZ detection. In addition, Se-CoO@GO-NC revealed fabulous catalytic reduction activity for DMZ, when compared to GO and Se-CoO modified GCE. Additionally, Se-CoO@GO-NC is applied in real sample analysis of pigeon egg, milk and pigeon meat. The results illustrated that Se-CoO@GO-NC can be a promising nanocomposite for the electrocatalytic reduction of DMZ in clinical samples in biomedical field.
在这项工作中，我们报告了一种新型硒纳米棒（Se）掺杂氧化钴（CoO）纳米花封装氧化石墨烯（GO）纳米复合材料（NC）的制备方法。成功地在 CoO 纳米花上修饰了 Se 纳米棒，并观察到 Se-CoO@GO-NC 的电导率增加。首次将制备的 Se-CoO@GO-NC 用作电化学传感器中二甲硝唑（DMZ）电化学检测的有效纳米复合材料。Se-CoO@GO-NC 修饰的玻碳电极（GCE）在 DMZ 传感时在较低的 -0.7314 V 下显示出优异的阴极电流响应（17.6 μA）。在各种优化条件下，基于 Se-CoO@GO-NC 的电化学传感器显示出 0.02-83.72 μM 的长线性范围、3.4 nM 的检测限和 1.898 μA.μM. cm 的灵敏度。此外，与 GO 和 Se-CoO 修饰的 GCE 相比，Se-CoO@GO-NC 对 DMZ 具有出色的催化还原活性。此外，Se-CoO@GO-NC 还应用于鸽子蛋、牛奶和鸽子肉的实际样品分析。结果表明，Se-CoO@GO-NC 可作为生物医学领域临床样品中 DMZ 电催化还原的有前途的纳米复合材料。
