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基于人群的希腊头痛致残调查:患病率、负担和治疗偏好。

A population-based survey for disabling headaches in Greece: Prevalence, burden and treatment preferences.

机构信息

Hellenic Headache Society, Athens, Greece.

Second Neurology Department, Attikon Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

出版信息

Cephalalgia. 2021 Jun;41(7):810-820. doi: 10.1177/0333102421989630. Epub 2021 Feb 1.

Abstract

OBJECTIVE

To estimate the prevalence, burden and current treatment of disabling primary headaches in a large sample of the Greek population aged 18-70 years old.

METHODS

This is an observational descriptive study, with cross-sectional design performed by quantitative computer-assisted telephone interviews, using a validated 37-item questionnaire for headaches. The prevalence, burden, and current treatment of primary headaches (ICHD-3) were recorded along with participants' treatment preferences.

RESULTS

Out of 10,008 interviewed participants, 1197 (12.0%) reported headaches affecting performance. The annual prevalence of migraine was 8.1% (95% confidence interval, 7.6-8.7, corresponding to 0.6 million Greeks), of chronic migraine 1.0% (95% confidence interval, 0.8-1.2, corresponding to 0.1 million), and of tension-type headache 3.8% (95% confidence interval, 3.4-4.2, corresponding to 0.3 million). The participants with headaches reported 0.5 headache-induced lost workdays per month (corresponding to 5.8 million lost workdays annually) and reductions in performance on 2.8 workdays per month (corresponding to 30.9 million workdays annually). In all, 43.4% of headache participants felt bad/ashamed because of headaches and 21.9% sought professional treatment, most often from a private neurologist. 83.8% of headache participants had never taken pharmacological prophylaxis, and only 5.5% were currently under preventative treatment. For both prophylactic and acute treatment, headache participants prefer oral medication to injection or stimulation devices.

CONCLUSION

More than 10% of the Greek adult population up to 70 years old experience disabling headaches, causing a dramatic work loss. More than 80% of these have never taken pharmacological prophylaxis. Thus, enriching the quality of life of people with headaches relies crucially on expanding awareness about headaches and their treatment.

摘要

目的

在一个 18-70 岁的希腊大样本人群中,评估致残性原发性头痛的患病率、负担和当前治疗情况。

方法

这是一项观察性描述性研究,采用横断面设计,通过定量计算机辅助电话访谈进行,使用经过验证的 37 项头痛问卷。记录原发性头痛(ICHD-3)的患病率、负担和当前治疗情况,以及参与者的治疗偏好。

结果

在接受访谈的 10008 名参与者中,有 1197 人(12.0%)报告头痛影响了工作表现。偏头痛的年患病率为 8.1%(95%置信区间,7.6-8.7,相当于 60 万希腊人),慢性偏头痛为 1.0%(95%置信区间,0.8-1.2,相当于 10 万人),紧张型头痛为 3.8%(95%置信区间,3.4-4.2,相当于 30 万人)。患有头痛的参与者每月报告 0.5 个因头痛导致的工作日缺勤(相当于每年 580 万工作日缺勤),每月有 2.8 个工作日因头痛而工作表现下降(相当于每年 3090 万工作日缺勤)。所有头痛患者中有 43.4%因头痛而感到不适/羞愧,21.9%寻求专业治疗,最常去私人神经科医生那里就诊。83.8%的头痛患者从未服用过预防性药物治疗,只有 5.5%的人目前正在接受预防性治疗。对于预防性和急性治疗,头痛患者更喜欢口服药物而不是注射或刺激设备。

结论

超过 10%的 70 岁以下希腊成年人口患有致残性头痛,导致工作效率显著下降。其中超过 80%的人从未服用过预防性药物治疗。因此,提高头痛患者的生活质量关键在于提高对头痛及其治疗的认识。

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