Department of Pediatric Allergy and Immunology, Gaziosmanpasa Education and Research Hospital, Istanbul, Turkey;
Department of Pediatrics, Bakirkoy Sadi Konuk Education and Research Hospital, Istanbul, Turkey.
Allergol Immunopathol (Madr). 2021 Jan 2;49(1):62-67. doi: 10.15586/aei.v49i1.16. eCollection 2021.
Papular urticaria is a hypersensitivity reaction characterized by chronic and recurrent papular erythema. It occurs as a result of the bites of mosquitoes, fleas, bed bugs, and other insects; and it is generally seen in children. This study examines the prevalence of atopic diseases in patients with papular urticaria.
The medical records of 130 pediatric patients with the diagnosis of papular urticaria between August 2017 and August 2019, whose disease progression was followed in two tertiary care centers, were reviewed retrospectively. The patients were divided into two groups: under 5 and above 5 years old. The prevalence of the atopic disease in children with papular urticaria was compared with those in age-matched controls without papular urticaria.
The study included 130 patients who were diagnosed with papular urticaria (64 males, 66 females, median age: 60 months). The prevalences of atopic disease, recurrent wheezing, and atopic dermatitis were higher in the group under 5 years old with papular urticaria than in the same-age control group (p=0.001, 0.002, and 0.001, respectively). The prevalences of atopic disease, asthma, allergic rhinitis, and atopic dermatitis were higher in the group above 5 years old with papular urticaria than in the same-age control group (p=0.001, 0.001, 0.001, and 0.007, respectively).
Many children with papular urticaria are atopic children. These patients should be assessed not only in terms of papular urticaria but also in terms of comorbid atopic diseases.
丘疹性荨麻疹是一种以慢性和复发性丘疹性红斑为特征的超敏反应。它是由蚊子、跳蚤、臭虫等昆虫叮咬引起的，通常见于儿童。本研究旨在探讨丘疹性荨麻疹患者特应性疾病的患病率。
回顾性分析了 2017 年 8 月至 2019 年 8 月在两家三级保健中心就诊并确诊为丘疹性荨麻疹的 130 例儿科患者的病历。将患者分为 5 岁以下和 5 岁以上两组。比较了丘疹性荨麻疹患儿与年龄匹配的无丘疹性荨麻疹对照组的特应性疾病患病率。
本研究共纳入 130 例诊断为丘疹性荨麻疹的患者（男 64 例，女 66 例，中位年龄 60 个月）。5 岁以下有丘疹性荨麻疹的患儿特应性疾病、反复喘息和特应性皮炎的患病率高于同年龄对照组（p=0.001、0.002 和 0.001）。5 岁以上有丘疹性荨麻疹的患儿特应性疾病、哮喘、过敏性鼻炎和特应性皮炎的患病率高于同年龄对照组（p=0.001、0.001、0.001 和 0.007）。
许多患有丘疹性荨麻疹的儿童都是特应性儿童。这些患者不仅要评估丘疹性荨麻疹，还要评估合并的特应性疾病。
