Radiation Oncology Department, University of Utah, Huntsman Cancer Institute, Salt Lake City, UH.
University College Hospital London, London, United Kingdom.
JCO Glob Oncol. 2021 Feb;7:173-182. doi: 10.1200/GO.20.00079.
Underdeveloped nations carry the burden of most cervical cancer, yet access to adequate treatment can be challenging. This report assesses the current management of cervical cancer in sub-Saharan Africa to better understand the needs of underdeveloped nations in managing cervical cancer.
A pre- and postsurvey was sent to all centers participating in the Cervical Cancer Research Network's 4th annual symposium. The pre- and postsurvey evaluated human papillomavirus and HIV screening, resources available for workup and/or treatment, treatment logistics, outcomes, and enrollment on clinical trials. Descriptive analyses were performed on survey responses.
Twenty-nine centers from 12 sub-Saharan countries saw approximately 300 new cases of cervical cancer yearly. Of the countries surveyed, 55% of countries had a human papillomavirus vaccination program and 30% (range, 0%-65%) of women in each region were estimated to have participated in a cervical cancer screening program. In the workup of patients, 43% of centers had the ability to obtain a positron emission tomography and computed tomography scan and 79% had magnetic resonance imaging capabilities. When performing surgery, 88% of those centers had a surgeon with an expertise in performing oncological surgeries. Radiation therapy was available at 96% of the centers surveyed, and chemotherapy was available in 86% of centers. Clinical trials were open at 4% of centers.
There have been significant advancements being made in screening, workup, and management of patients with cervical cancer in sub-Saharan Africa; yet, improvement is still needed. Enrollment in clinical trials remains a struggle. Participants would like to enroll patients on clinical trials with Cervical Cancer Research Network's continuous support.
发展中国家承担了大多数宫颈癌负担，但获得足够的治疗可能具有挑战性。本报告评估了撒哈拉以南非洲地区宫颈癌的当前管理情况，以便更好地了解发展中国家在管理宫颈癌方面的需求。
向参加宫颈癌研究网络第四次年度研讨会的所有中心发送了一份预调查和一份后调查。预调查和后调查评估了人乳头瘤病毒和艾滋病毒筛查、用于检查和/或治疗的可用资源、治疗后勤、结果以及临床试验的入组情况。对调查结果进行了描述性分析。
来自 12 个撒哈拉以南国家的 29 个中心每年诊治约 300 例新的宫颈癌病例。在所调查的国家中，55%的国家有 HPV 疫苗接种计划，估计每个地区有 30%（范围为 0%-65%）的女性参加了宫颈癌筛查计划。在对患者进行检查时，43%的中心有能力获得正电子发射断层扫描和计算机断层扫描，79%的中心有磁共振成像能力。在进行手术时，88%的中心有擅长进行肿瘤手术的外科医生。96%的调查中心提供放射治疗，86%的中心提供化疗。4%的中心有临床试验开放。
在撒哈拉以南非洲，宫颈癌的筛查、检查和管理方面取得了重大进展；然而，仍需要改进。临床试验的入组仍然是一个挑战。参与者希望在宫颈癌研究网络的持续支持下，让患者参加临床试验。
