Post-Graduate Program in Dentistry, Federal University of Pelotas, Pelotas, Brazil.
Post-Graduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.
Oral Dis. 2022 Sep;28(6):1733-1740. doi: 10.1111/odi.13789. Epub 2021 Feb 16.
This study investigated the role of oral health self-perception as mediator of association between dental caries and depression among pregnant women from the 2015 Pelotas Birth Cohort Study, Brazil.
Overall, 2,496 pregnant women participated of this oral health sub-study. Data related to demographic and socioeconomic conditions, lifetime and current depression, and oral health self-perception were collected. Participants were also assessed for dental caries (DMF-T index). Depression was assessed using the Edinburgh Postnatal Depression Scale. For analysis, six outcomes related to dental caries experience were considered. Causal mediation analysis was performed using parametric regression models.
When it was assumed that all subjects had poor perception about oral health, it was observed that the presence of moderate/severe depressive signals and symptoms was higher in subjects with dental caries experience (OR 1.13; CI 95% 1.06-1.20), with severity of untreated dental caries (OR 2.08; CI 95% 1.16-3.78), untreated dental caries (OR 1.18; 95% CI 1.07-1.29), tooth loss (OR 1.08; 95% CI 1.02-1.14), and filled tooth (OR 1.07; 95% CI 1.02-1.16).
Our findings show the effect of dental caries on depression is mediated by self-perception about oral health in pregnant women.
本研究调查了口腔健康自我感知在巴西 2015 年佩洛塔斯出生队列研究中孕妇龋齿和抑郁之间关联中的中介作用。
共有 2496 名孕妇参加了这项口腔健康子研究。收集了与人口统计学和社会经济状况、终生和当前抑郁以及口腔健康自我感知相关的数据。还对参与者进行了龋齿（DMF-T 指数）评估。抑郁使用爱丁堡产后抑郁量表进行评估。在分析中，考虑了与龋齿经历相关的六个结果。使用参数回归模型进行因果中介分析。
当假设所有受试者对口腔健康的感知都较差时，发现有龋齿经历的受试者中存在中度/重度抑郁信号和症状的比例更高（OR 1.13；95%CI 1.06-1.20），未治疗龋齿的严重程度（OR 2.08；95%CI 1.16-3.78）、未治疗龋齿（OR 1.18；95%CI 1.07-1.29）、牙齿缺失（OR 1.08；95%CI 1.02-1.14）和填充牙（OR 1.07；95%CI 1.02-1.16）。
我们的研究结果表明，龋齿对抑郁的影响是通过孕妇对口腔健康的自我感知来介导的。
