美国成年人的抑郁与龋齿：NHANES 2015-2018。

Depression and dental caries in US adults, NHANES 2015-2018.

机构信息

Department of Stomatology, Second Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang, China.

Department of Stomatology, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China.

出版信息

BMC Oral Health. 2024 May 2;24(1):520. doi: 10.1186/s12903-024-04288-5.

DOI:10.1186/s12903-024-04288-5

PMID:38698375

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11067126/

Abstract

PURPOSE

This study aimed to investigate the link between depression and untreated dental caries among adults in the United States.

METHODS

Data were collected from the National Health and Nutrition Survey (2015-2018); respondents aged 20 years or older who completed a patient health questionnaire and underwent a comprehensive oral examination were included. Participants were categorized into three groups according to depressive symptoms as follows: those with no, mild, or moderate to severe depression. Data were weighted, and multiple potential covariates were included in the analysis to provide national estimates and account for the complex sample design. A multivariable weighted logistic regression model was performed to test the hypothesis that varying degrees of depression in American adults are associated with untreated dental caries. Subgroup analyses were performed based on age and gender after adjusting for potential covariates. A P value of <.05 was considered significant.

RESULTS

Among 8740 participants, the prevalence of untreated coronal and root caries was 20.50% and 12.92%, respectively. Moderate to severe depression was a significant risk factor (odds ratio, 1.25; 95% confidence interval, 1.09-1.66) for untreated root caries. The risk of untreated root caries increased by 87% in young adults (aged 20-44 years) and by 46% in women with moderate to severe depression. The suest analysis revealed that the impact of moderate to severe depressive disorder on untreated root caries was non-significantly different between the age subgroup (p=0.09) and sex subgroup (p=0.51). However, depression was non-significantly associated with untreated coronal caries (mild depression: OR, 1.07; 95% CI, 0.85-1.34; moderate to severe depression 1.06; 95% CI, 0.83-1.36; respectively).

CONCLUSION

The results of this study suggested a significant association between moderate and severe depression and untreated root caries; however, the association with untreated coronal caries was non-significant. In the United States, moderate and severe depression in adults is associated with root caries.

摘要

目的

本研究旨在探讨美国成年人抑郁与未经治疗的龋齿之间的关系。

方法

数据来自国家健康与营养调查（2015-2018 年）；纳入年龄在 20 岁及以上、完成患者健康问卷并接受全面口腔检查的受访者。根据抑郁症状将参与者分为三组：无、轻度或中重度抑郁。数据经过加权处理，并纳入多个潜在混杂因素进行分析，以提供全国估计值，并考虑到复杂的样本设计。采用多变量加权逻辑回归模型检验假设，即美国成年人不同程度的抑郁与未经治疗的龋齿有关。在调整潜在混杂因素后，根据年龄和性别进行亚组分析。P 值<.05 为差异有统计学意义。

结果

在 8740 名参与者中，未经治疗的冠部和根部龋齿的患病率分别为 20.50%和 12.92%。中重度抑郁是未经治疗的根龋的显著危险因素（比值比，1.25；95%置信区间，1.09-1.66）。年轻人（20-44 岁）中重度抑郁患者的未经治疗的根龋风险增加了 87%，女性则增加了 46%。敏感性分析显示，中重度抑郁障碍对未经治疗的根龋的影响在年龄亚组（p=0.09）和性别亚组（p=0.51）之间无显著差异。然而，抑郁与未经治疗的冠部龋齿无显著相关性（轻度抑郁：OR，1.07；95%CI，0.85-1.34；中重度抑郁：OR，1.06；95%CI，0.83-1.36）。