两株小鼠中胆碱能药物反应的年龄依赖性差异。
Age-dependent differences in cholinergic drug response in two strains of mice.
作者信息
Castellano C, Oliverio A, Schwab C, Brueckner G, Biesold D
机构信息
Istituto di Psicobiologia e Psicofarmacologia del CNR, Rome, Italy.
出版信息
Neurosci Lett. 1988 Feb 3;84(3):335-8. doi: 10.1016/0304-3940(88)90531-9.
PMID:3352959
Abstract
The behavioral effects of nicotine and oxotremorine were assessed in two strains of mice, C57BL/6 (C57) and DBA/2 (DBA), differing in the ontogeny of forebrain cholinergic structures. Both nicotine and oxotremorine depressed to a higher extent the behavior of DBA mice starting at day 45 of postnatal life.
摘要
在两种品系的小鼠C57BL/6（C57）和DBA/2（DBA）中评估了尼古丁和氧化震颤素的行为效应，这两种品系在前脑胆碱能结构的个体发生上存在差异。从出生后第45天开始，尼古丁和氧化震颤素都更强烈地抑制了DBA小鼠的行为。
相似文献
1
Age-dependent differences in cholinergic drug response in two strains of mice.两株小鼠中胆碱能药物反应的年龄依赖性差异。
Neurosci Lett. 1988 Feb 3;84(3):335-8. doi: 10.1016/0304-3940(88)90531-9.
2
Developmental differences of antinociceptive effects of oxotremorine in two inbred strains of mice.氧化震颤素对两种近交系小鼠伤害性感受抑制作用的发育差异
Brain Res Dev Brain Res. 1989 Sep 1;49(1):156-60. doi: 10.1016/0165-3806(89)90071-0.
3
Genetic influences on cholinergic drug response.遗传因素对胆碱能药物反应的影响。
Pharmacol Biochem Behav. 1981 Aug;15(2):271-9. doi: 10.1016/0091-3057(81)90187-8.
4
Age-related cholinergic drug effects on analgesia in two inbred strains of mice.年龄相关的胆碱能药物对两种近交系小鼠镇痛作用的影响。
Brain Res. 1990 Feb 26;510(1):150-3. doi: 10.1016/0006-8993(90)90743-u.
5
Serotonergic influence on cholinergic-induced analgesia: differences in two inbred strains of mice.
Brain Res. 1992 Apr 17;577(2):347-50. doi: 10.1016/0006-8993(92)90296-l.
6
Effects of acute and chronic stress and of genotype on oxotremorine-induced locomotor depression of mice.急性和慢性应激以及基因型对氧化震颤素诱导的小鼠运动抑制的影响。
Behav Neural Biol. 1991 Jan;55(1):123-30. doi: 10.1016/0163-1047(91)80132-x.
7
Influences of genotype and sex on behavioral tolerance to nicotine in mice.
Pharmacol Biochem Behav. 1977 Jan;6(1):25-30. doi: 10.1016/0091-3057(77)90156-3.
8
Differences in behavioral responses to oxotremorine and physostigmine in New Zealand black (NZB/BlNJ) and C57BL/6 mice.新西兰黑鼠（NZB/BlNJ）和C57BL/6小鼠对氧化震颤素和毒扁豆碱行为反应的差异。
Neuropharmacology. 1987 May;26(5):445-52. doi: 10.1016/0028-3908(87)90025-6.
9
Genetics of nicotine response in four inbred strains of mice.四种近交系小鼠尼古丁反应的遗传学
J Pharmacol Exp Ther. 1983 Jul;226(1):291-302.
10
The influence of genotype and sex on behavioral sensitivity to nicotine in mice.基因型和性别对小鼠尼古丁行为敏感性的影响。
Psychopharmacology (Berl). 1980;71(1):45-9. doi: 10.1007/BF00433251.
引用本文的文献
1
Different levels of acetylcholinesterase and choline acetyltransferase activities in C57Bl/6 and DBA/2 mice are not accompanied with different density of cortical acetylcholinesterase reactive fibers.C57Bl/6和DBA/2小鼠中不同水平的乙酰胆碱酯酶和胆碱乙酰转移酶活性，并未伴随着皮质乙酰胆碱酯酶反应性纤维密度的差异。
Neurochem Res. 1990 Nov;15(11):1127-33. doi: 10.1007/BF01101715.
2
Autoradiography of muscarinic cholinergic receptors in cortical and subcortical brain regions of C57BL/6 and DBA/2 mice.C57BL/6和DBA/2小鼠大脑皮质和皮质下区域毒蕈碱型胆碱能受体的放射自显影
Neurochem Res. 1992 Nov;17(11):1057-62. doi: 10.1007/BF00967281.
Zotero 插件