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生物合成银纳米粒子在抗菌机制中的作用。

The Role of Biosynthesized Silver Nanoparticles in Antimicrobial Mechanisms.

机构信息

Numpex-Bio, Universidade Federal do Rio de Janeiro (UFRJ), Campus Duque de Caxias, Duque de Caxias, Brazil.

Centro de Ciências Naturais e Humanas, Universidade Federal do ABC (UFABC), Santo Andre, Brazil.

出版信息

Curr Pharm Biotechnol. 2021;22(6):762-772. doi: 10.2174/1389201022666210202143755.

Abstract

Nanotechnology is an area of science in which new materials are developed. The correlation between nanotechnology and microbiology is essential for the development of new drugs and vaccines. The main advantage of combining these areas is to associate the latest technology in order to obtain new ways for solving problems related to microorganisms. This review seeks to investigate nanoparticle formation's antimicrobial properties, primarily when connected to the green synthesis of silver nanoparticles. The development of new sustainable methods for nanoparticle production has been instrumental in designing alternative, non-toxic, energy-friendly, and environmentally friendly routes. In this sense, it is necessary to study silver nanoparticles' green synthesis concerning their antimicrobial properties. Antimicrobial silver nanoparticles' mechanisms demonstrate efficiency to gram-positive bacteria, gram-negative bacteria, fungi, viruses, and parasites. However, attention is needed with the emergence of resistance to these antimicrobials. This article seeks to relate the parameters of green silver- based nanosystems with the efficiency of antimicrobial activity.

摘要

纳米技术是一门开发新材料的科学。纳米技术与微生物学的相关性对于开发新的药物和疫苗至关重要。将这些领域结合起来的主要优势是将最新技术联系起来,以获得解决与微生物有关的问题的新途径。本综述旨在研究纳米颗粒形成的抗菌特性,主要是当与银纳米颗粒的绿色合成相结合时。开发新的可持续纳米颗粒生产方法对于设计替代、无毒、节能和环保的途径至关重要。在这方面,有必要研究银纳米颗粒的绿色合成及其抗菌特性。抗菌银纳米颗粒的作用机制对革兰氏阳性菌、革兰氏阴性菌、真菌、病毒和寄生虫都有效。然而,需要注意的是,这些抗菌药物的耐药性正在出现。本文试图将绿色银基纳米系统的参数与抗菌活性的效率联系起来。

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