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梭形细胞肉瘤:自发性气胸的罕见病因。

Spindle cell sarcoma: a rare cause of a spontaneous pneumothorax.

作者信息

Pedroso Ana, Beckert Lutz

机构信息

Department of Respiratory Medicine Canterbury District Health Board Christchurch New Zealand.

Serviço de Medicina Hospital de São Francisco Xavier (Centro Hospitalar Lisboa Ocidental) Lisboa Portugal.

出版信息

Respirol Case Rep. 2021 Jan 25;9(3):e00709. doi: 10.1002/rcr2.709. eCollection 2021 Mar.

DOI:10.1002/rcr2.709
PMID:33532073
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7829631/
Abstract

Secondary spontaneous pneumothoraces are associated with a variety of lung disorders. Malignancy is a rare cause of a pneumothorax and rarely the presenting feature. Cavitating primary tumours are less frequent causes of pneumothoraces than secondary tumours. We present the case of an asymptomatic spontaneous pneumothorax in a 71-year-old never-smoking woman. Her right apical pneumothorax was diagnosed by chance on a chest radiograph for a fall. Her final diagnosis was a primary spindle cell sarcoma of the pleura. This case demonstrates the need to explore the underlying causes of a non-resolving pneumothorax. The early diagnosis of her sarcoma allowed curative treatment.

摘要

继发性自发性气胸与多种肺部疾病相关。恶性肿瘤是气胸的罕见病因,很少作为首发症状出现。与继发性肿瘤相比,有空洞形成的原发性肿瘤导致气胸的情况较少见。我们报告一例71岁从不吸烟女性的无症状自发性气胸病例。她因跌倒进行胸部X线检查时偶然发现右肺尖气胸。最终诊断为胸膜原发性梭形细胞肉瘤。该病例表明,对于持续性气胸需要探究其潜在病因。她的肉瘤早期诊断使得能够进行根治性治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7808/7829631/4975e8bd7414/RCR2-9-e00709-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7808/7829631/49759a86ba80/RCR2-9-e00709-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7808/7829631/4975e8bd7414/RCR2-9-e00709-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7808/7829631/49759a86ba80/RCR2-9-e00709-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7808/7829631/4975e8bd7414/RCR2-9-e00709-g002.jpg

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本文引用的文献

1
Spindle cell sarcoma: a SEER population-based analysis.梭形细胞肉瘤:一项 SEER 基于人群的分析。
Sci Rep. 2018 Mar 22;8(1):5024. doi: 10.1038/s41598-018-23145-4.
2
WHO classification of soft tissue tumours: an update based on the 2013 (4th) edition.世界卫生组织软组织肿瘤分类:基于 2013 年(第 4 版)的更新。
Pathology. 2014 Feb;46(2):95-104. doi: 10.1097/PAT.0000000000000050.
3
A comprehensive review of spontaneous pneumothorax complicating sarcoma.自发性气胸并发肉瘤的全面综述。
Chest. 2010 Sep;138(3):510-8. doi: 10.1378/chest.09-2292. Epub 2010 Apr 9.
4
Spontaneous pneumothorax. A complication of lung cancer?自发性气胸。肺癌的一种并发症?
Chest. 1985 Nov;88(5):709-13. doi: 10.1378/chest.88.5.709.
5
Spontaneous pneumothorax and pulmonary malignant disease--a syndrome sometimes associated with cavitating tumours. Report of nine new cases, four with metastases and five with primary bronchial tumours.自发性气胸与肺部恶性疾病——一种有时与空洞性肿瘤相关的综合征。9例新病例报告,4例有转移,5例有原发性支气管肿瘤。
Clin Radiol. 1976 Apr;27(2):211-22. doi: 10.1016/s0009-9260(76)80148-1.