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使用预切割骨软骨异体移植塞和微粉化细胞外软骨增强技术进行供区回填的膝关节局灶性软骨损伤自体骨软骨移植术

Osteochondral Autograft Transfer for Focal Cartilage Lesions of the Knee With Donor-Site Back-Fill Using Precut Osteochondral Allograft Plugs and Micronized Extracellular Cartilage Augmentation.

作者信息

Vellios Evan E, Jones Kristofer J, Williams Riley J

机构信息

Sports Medicine and Shoulder Surgery Service, Hospital for Special Surgery, New York, New York.

Department of Orthopaedic Surgery, Division of Sports Medicine and Shoulder Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California, U.S.A.

出版信息

Arthrosc Tech. 2021 Jan 20;10(1):e181-e192. doi: 10.1016/j.eats.2020.09.025. eCollection 2021 Jan.

DOI:10.1016/j.eats.2020.09.025
PMID:33532227
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7823117/
Abstract

Osteochondral autograft transfer (OAT) allows for the treatment of focal chondral lesions of the femoral condyles. Patients undergoing OAT have been shown to have the greatest rate and quickest return to sport of any cartilage-restoration procedure. Disadvantages encountered with the OAT procedure include limited donor sources, small treatable lesion size, and donor-site morbidity. Here, we describe our preferred technique of open OAT with donor-site back-filling using precut fresh osteochondral allograft plugs and micronized extracellular cartilage augmentation. Advantages to this technique include single-stage transfer of living autologous osteochondral grafts allowing for early ambulation, predictable return to sport, enhanced long-term graft survival, and decreased donor-site morbidity secondary to fresh osteochondral allograft back-fill.

摘要

自体骨软骨移植（OAT）可用于治疗股骨髁的局灶性软骨损伤。接受OAT治疗的患者在所有软骨修复手术中恢复运动的比例最高且恢复速度最快。OAT手术存在的缺点包括供体来源有限、可治疗的损伤面积小以及供体部位的并发症。在此，我们描述了一种开放式OAT的首选技术，即使用预先切割的新鲜骨软骨同种异体移植栓进行供体部位回填以及微粉化细胞外软骨增强。该技术的优点包括单阶段移植活的自体骨软骨移植物，允许早期下床活动、可预测的运动恢复、提高移植物长期存活率，以及因新鲜骨软骨同种异体移植回填而降低供体部位并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/7823117/e92fb9a37403/gr17.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/7823117/22087118def6/gr10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/7823117/64e6abd285dd/gr11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/7823117/04ece4491969/gr12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/7823117/e819455be42a/gr13.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/7823117/e92fb9a37403/gr17.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/7823117/1290267a8ff2/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/7823117/1f91f9ed034e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/7823117/b34482a3ee09/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/7823117/bd79094ea27e/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/7823117/69721e6fcd45/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/7823117/2c7184a002ef/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/7823117/53fb56668d6a/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/7823117/ba0a92e9c6be/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/7823117/5a455db18f1b/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/7823117/22087118def6/gr10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/7823117/64e6abd285dd/gr11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/7823117/04ece4491969/gr12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/7823117/e819455be42a/gr13.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/7823117/11fe0dfaa0cd/gr14.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/7823117/fa2c55c275b6/gr15.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/7823117/aacb94e3a322/gr16.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bdd/7823117/e92fb9a37403/gr17.jpg

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