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新鲜预切割骨软骨异体移植核心移植术治疗股骨软骨缺损

Fresh Precut Osteochondral Allograft Core Transplantation for the Treatment of Femoral Cartilage Defects.

作者信息

Jones Kristofer J, Mosich Gina M, Williams Riley J

机构信息

Department of Orthopaedic Surgery, Division of Sports Medicine and Shoulder Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California, U.S.A.

Sports Medicine and Shoulder Service, Hospital for Special Surgery, New York, New York, U.S.A.

出版信息

Arthrosc Tech. 2018 Jul 2;7(8):e791-e795. doi: 10.1016/j.eats.2018.03.016. eCollection 2018 Aug.

DOI:10.1016/j.eats.2018.03.016
PMID:30167355
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6111451/
Abstract

Fresh osteochondral allograft (OCA) transplantation is a successful single-stage procedure for the treatment of symptomatic cartilage defects of the knee. Although long-term studies reveal reliable improvements in patient-reported outcome scores and graft survival, the limitations of the procedure include graft availability and timely use prior to expiration. To avoid prolonged surgical wait times and progression of lesion size, some surgeons have employed the use of nonorthotopic grafts (e.g., lateral femoral condyle graft for a medial femoral condyle lesion). Additionally, fresh precut OCA cores can be used for smaller symptomatic lesions, thereby precluding surgical delays associated with donor-recipient size matching. We describe our preferred technique for the use of fresh precut OCA cores for the treatment of small osteochondral defects of the knee. The distinct advantages of this technique include single-stage restoration of the articular surface without the donor site morbidity observed with osteochondral autograft transplantation.

摘要

新鲜骨软骨异体移植(OCA)是治疗膝关节有症状软骨缺损的一种成功的单阶段手术。尽管长期研究显示患者报告的结局评分和移植物存活率有可靠改善,但该手术的局限性包括移植物的可获得性以及在过期前及时使用。为避免手术等待时间过长和病变大小进展,一些外科医生采用了非原位移植物(例如,用外侧股骨髁移植物治疗内侧股骨髁病变)。此外,新鲜预切割的OCA核心可用于较小的有症状病变,从而避免与供体 - 受体尺寸匹配相关的手术延迟。我们描述了我们使用新鲜预切割OCA核心治疗膝关节小骨软骨缺损的首选技术。该技术的独特优势包括关节面的单阶段修复,而不会出现自体骨软骨移植中观察到的供体部位并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e61a/6111451/3a01a07f7b71/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e61a/6111451/0eb6e5b70ff1/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e61a/6111451/3a01a07f7b71/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e61a/6111451/0eb6e5b70ff1/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e61a/6111451/3a01a07f7b71/gr2.jpg

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本文引用的文献

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Condyle-Specific Matching Does Not Improve Midterm Clinical Outcomes of Osteochondral Allograft Transplantation in the Knee.髁特异性匹配并不能改善膝关节同种异体骨软骨移植的中期临床结果。
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Return to Sport and Recreational Activity After Osteochondral Allograft Transplantation in the Knee.膝关节同种异体骨软骨移植术后恢复运动和娱乐活动
Am J Sports Med. 2017 Jun;45(7):1608-1614. doi: 10.1177/0363546517694857. Epub 2017 Apr 4.
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Medial Femoral Condyle Cartilage Defect Biomechanics: Effect of Obesity, Defect Size, and Cartilage Thickness.
Design and Fabrication of Micro Saw Enabling Root-Side Cutting of Bone.用于骨根侧切割的微型锯的设计与制造
Micromachines (Basel). 2023 Apr 15;14(4):856. doi: 10.3390/mi14040856.
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Harvest Technique Does Affect the Quality of Osteochondral Grafts: Histologic Evaluation Comparing Commercial Standards versus Scalpel Blade Technique. Harvest 技术确实会影响骨软骨移植物的质量:比较商业标准与手术刀技术的组织学评估。
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