基于三维声学分辨率的动态聚焦光声内镜检查
3D acoustic resolution-based photoacoustic endoscopy with dynamic focusing.
作者信息
Wang Bo, Wang Congcong, Zhong Fangyi, Pang Weiran, Guo Lili, Peng Kuan, Xiao Jiaying
机构信息
Department of Biomedical Engineering, Central South University, Changsha, China.
Department of Biomedical Engineering, Guangzhou Huaxia Vocational College, Guangzhou, China.
出版信息
Quant Imaging Med Surg. 2021 Feb;11(2):685-696. doi: 10.21037/qims-20-625.
BACKGROUND
Acoustic resolution-based photoacoustic endoscopy (ARPAE) is a non-invasive potential tool for imaging gastrointestinal and urogenital tracts. However, current ARPAE systems usually only provide 2D sectorial B-mode images, and have the limitation of the image quality significantly deteriorating out-of-focus regions due to transducers with fixed focus in these systems. To overcome these limitations, we put forward a modified back-projection method that can provide 3D images with dynamic focusing in ARPAE.
METHODS
A graphics processing unit (GPU)-based parallel computation technique was adopted for efficient computation. Both simulated and phantom/ex-vivo experiments were conducted to validate our method.
RESULTS
The findings indicated that our proposed method can effectively improve the lateral resolution and signal-to-noise ratio (SNR) in the out-of-focus regions. For a target 3 mm from the transducer focus, the new method can improve 11 times in the lateral resolution, along with an improvement of up to 37 dB in the SNR.
CONCLUSIONS
3D ARPAE provides high-quality imaging in both focus and out-of-focus regions.
背景
基于声学分辨率的光声内镜（ARPAE）是一种用于胃肠道和泌尿生殖道成像的无创性潜在工具。然而，目前的ARPAE系统通常仅提供二维扇形B模式图像，并且由于这些系统中换能器具有固定焦点，存在离焦区域图像质量显著下降的局限性。为了克服这些局限性，我们提出了一种改进的反投影方法，该方法可以在ARPAE中提供具有动态聚焦的三维图像。
方法
采用基于图形处理单元（GPU）的并行计算技术进行高效计算。进行了模拟实验和体模/离体实验以验证我们的方法。
结果
研究结果表明，我们提出的方法可以有效提高离焦区域的横向分辨率和信噪比（SNR）。对于距离换能器焦点3毫米的目标，新方法可以将横向分辨率提高11倍，同时信噪比提高高达37分贝。
结论
三维ARPAE在聚焦和离焦区域均能提供高质量成像。
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