BAGET 2.0：一款用于轻松检索原核生物基因背景和序列的更新网络工具。
BAGET 2.0: an updated web tool for the effortless retrieval of prokaryotic gene context and sequence.
作者信息
Hepp Benjamin, Da Cunha Violette, Lorieux Florence, Oberto Jacques
机构信息
Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), 91198, Gif-sur-Yvette, France.
出版信息
Bioinformatics. 2021 Sep 9;37(17):2750-2752. doi: 10.1093/bioinformatics/btab082.
MOTIVATION
The retrieval of a single gene sequence and context from completely sequenced bacterial and archaeal genomes constitutes an intimidating task for the wet bench biologist. Existing web-based genome browsers are either too complex for routine use or only provide a subset of the available prokaryotic genomes.
RESULTS
We have developed BAGET 2.0 (Bacterial and Archaeal Gene Exploration Tool), an updated web service granting access in just three mouse clicks to the sequence and synteny of any gene from completely sequenced bacteria and archaea. User-provided annotated genomes can be processed as well. BAGET 2.0 relies on a local database updated on a daily basis.
AVAILABILITY AND IMPLEMENTATION
BAGET 2.0 befits all current browsers such as Chrome, Firefox, Edge, Opera and Safari. Internet Explorer 11 is supported. BAGET 2.0 is freely accessible at https://archaea.i2bc.paris-saclay.fr/baget/.
动机
从完全测序的细菌和古菌基因组中检索单个基因序列及其背景信息，对于实验台生物学家来说是一项艰巨的任务。现有的基于网络的基因组浏览器要么过于复杂，不适合常规使用，要么只提供了可用原核生物基因组的一个子集。
结果
我们开发了BAGET 2.0（细菌和古菌基因探索工具），这是一个更新后的网络服务，只需点击三下鼠标，就能获取完全测序的细菌和古菌中任何基因的序列和共线性信息。用户提供的注释基因组也可以进行处理。BAGET 2.0依赖于一个每天更新的本地数据库。
可用性与实现
BAGET 2.0适用于所有当前的浏览器，如Chrome、Firefox、Edge、Opera和Safari。支持Internet Explorer 11。可通过https://archaea.i2bc.paris-saclay.fr/baget/免费访问BAGET 2.0。
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